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Yayın Approach to neck in early stage lip cancers(Sakarya University, 2017) Demir, Deniz; Genç, Sena; Güven, Mehmet; Yılmaz, Mahmut Sinan; Kara, Ahmet; Demir, DenizAMAÇ Bu çalışmanın amacı, erken evre dudak kanseri hastalarında, bekle-gör politikasının ve boyun diseksiyonunun prognoz üzerindeki rolünü araştırmaktır. GEREÇ - YÖNTEMLER: Mart 2007 - Nisan 2015 yılları arasında T1-2N0 alt dudak kanseri nedeniyle primer bölge ve boyun cerrahisi yapılan 20 hasta (5 kadın, 15 erkek; yaş ortalaması 62.64 yıl; 38-80 yaş aralığı) çalışmaya dahil edildi. Klinik özellikler, lezyonun lokalizasyonu, bölgesel lenf nodu durumu, tümör evrelemesi, cerrahi tedavi sonuçları ve patolojik inceleme verileri geriye dönük olarak incelendi. Tüm olgularda 1 cm cerrahi sınırla tümör eksize edildi. Doku defekti birincil kapatma ya da çeşitli rekonstriksiyon teknikleri ile onarıldı. Tüm T2N0 evre hastalara boyun diseksiyonu uygulandı. Tümör dudağın ortasında yer alıyorsa, bilateral boyun diseksiyonu, aksi taktirde tek taraflı boyun diseksiyonu yapıldı. BULGULAR: Her olguda histopatolojik tanı skuamöz hücreli karsinomdu. Ortalama izlem süresi 45.82 ay idi. Klinik olarak T1N0 tümörü tanısı konan 15 hasta ve klinik olarak T2N0 tümörü tanısı konan 5 hasta vardı. T1N0 tümörleri için 3 suprahyoid, 2 bilateral supraomohyoid boyun diseksiyonu yapıldı. Üç T2N0 tümöründe supraomohyoid boyun disseksiyonu bilateral olarak yapıldı ve geriye kalan 2 hastada suprahyoid boyun diseksiyonu yapıldı. SONUÇ: Hastalıksız dört yıllık sağ kalım oranları, erken evre dudak kanseri vakalarında belirgin olarak daha yüksekti. Sonuçlarımız T1N0 alt dudak kanserlerinde boyun diseksiyonunun gerekli olmayabileceğini göstermektedir.Yayın Are calculated ratios and red blood cell and platelet distribution width really important for the laryngeal cancer and precancerous larynx lesions(Wolters Kluwer, 2019) Kara, Ahmet; Güven, Mehmet; Demir, Deniz; Yılmaz, Mahmut Sinan; Gündoğan, M.E.; Genç, Sena; Demir, DenizIntroduction: In this research, it is planned to investigate the differences in neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, lymphocyte-to-monocyte ratio, reticulocyte distribution width, and platelet distribution width values of groups of benign laryngeal lesion, precancerous laryngeal lesion, and laryngeal squamous cell carcinoma and among patients with different stages of tumors in laryngeal carcinoma and precancerous laryngeal lesion groups, and whether these values carry a prognostic features. Materials and Methods: The investigated parameters determined from preoperative blood samples of patients have been compared among the groups and in the subgroups according to severity of illness in laryngeal carcinoma and precancerous laryngeal lesion groups. Also, the laryngeal carcinoma and precancerous laryngeal lesion groups were divided into two subgroups as good and poor prognosis and were compared with patients having good prognosis requiring no additional treatment during the follow-up, and the statistical significance of the differences was examined. Results: On comparison, statistically significant differences were only observed between the gross larynx carcinoma group and other lesions. Apart from that, when the values were evaluated in terms of prognosis, no significant statistical results were found in any of the values. Conclusion: Despite the significant statistical results seen in the gross tumors, it is known that there are more objective methods for identifying those lesions in clinical use. We conclude that caution should be exercised when using these new hematological parameters, which can be affected by many factors.Yayın Are neutrophil, platelet and eosinophil-to-lymphocyte ratio and red blood cell distribution width can be used for nasal polyposis?(Springerlink, 2017) Kara, Ahmet; Güven, Mehmet; Yılmaz, Mahmut Sinan; Demir, Deniz; Elden, Halil; Demir, DenizIntroduction The aim of this study is to explore the relationship of neutrophil, platelet and eosinophil-to-lymphocyte ratios and red blood cell distribution width values with nasal polyposis, and whether this could be a predictive parameter that can be used for the severity and recurrence risk of the disease. Method Neutrophil/lymphocyte, platelet/lymphocyte, eosinophil/lymphocyte ratios and red blood cell distribution width values were compared between nasal polyposis patients who were reviewed in a retrospective manner and the control group comparable for age and sex. Moreover, the nasal polyposis group was grouped for nasal polyposis severity and recurrence, and these subgroups were statistically compared, too. Results When the nasal polyposis patient group and the control group are compared, no statistically significant difference was found between two groups except for eosinophil/lymphocyte ratio. While only the difference between nasal polyposis severity and eosinophil/lymphocyte ratio is statistically significant, there was no parameter with statistically significant difference for recurrence. Conclusion We think that caution should be exercised when using these new hematological parameters which can be affected by many factors for the presence, severity and recurrence risk of nasal polyposis, and literature data should be proven by conducting different and objective studies on this subject.Yayın Assessment of the factors that affect the anatomic and functional success of cartilage tympanoplasty in children(Wolters Kluwer, 2017) Yılmaz, Mahmut Sinan; Kara, Ahmet; Güven, Mehmet; Demir, Deniz; Erkorkmaz, Ünal; Demir, DenizObjectives: Many factors may influence the surgical outcome of tympanoplasty in children, including age, the size and location of perforation, otorrhea, status of contralateral ear, surgical technique, and adenoid hypertrophy. This study aims to evaluate the outcomes of pediatric cartilage tympanoplasty and to assess the factors that affect the success of tympanoplasty in children. Methods: Children with chronic otitis media who underwent tympanoplasty using cartilage as graft material were evaluated retrospectively. Patient age, gender, size and site of the perforation, status of the contralateral ear, preoperative and postoperative hearing levels, surgical technique, and postoperative complications were noted. Results: Of the 72 patients included in the study, 27 were male and 35 were female. The average age was 13.22 ± 2.64 and mean follow-up time was 18.4 ± 8.62 months. Anatomic and functional success rates were 88.8% and 80.6%, respectively. Age, gender, and the status of the contralateral ear had no effect on surgical success rate. The mean preoperative and postoperative pure-tone averages were 33.2 6± 10.37 and 21.00 ± 13.25 dB, respectively. Conclusion: Anatomic and functional outcomes of cartilage tympanoplasty are quite satisfactory in pediatric patients. Chronic otitis media should be treated surgically as early as when patient cooperation is possible.Yayın Clinical results of surgical treatment in parotid tumors(Medcrave, 2017) Kara, Ahmet; Yılmaz, Mahmut Sinan; Demir, Deniz; Genç, Sena; Güven, Ebru Mihriban; Demir, DenizObjective: In this study, we aimed to evaluate clinical presentations, histopathological diagnosis, surgical treatment modalities and complications of patients operated for a parotid gland mass. Methods: Medical records of 100 patients who were operated for a parotid gland mass between 2010 and 2016 years evaluated retrospectively. Results and discussion: 49 (49%) of these patients were female and 51 (51%) were male. The mean age of the patients was 47.9. Post-operative histopathologic assessement, 89 of the cases were found to be primary benign, 7 of the cases primary malignant and 4 of the cases secondary malignant. For benign tumors the most common histopathology was pleomorphic adenoma in 45 (45%) patients, and the second was whartin tumor in 32 (32%) patients. Mucoepidermoid carsinoma was seen as the most common primary malign tumor (3 patients). All cases with primary malignancy continue to follow-up visits and the average follow-up period is 37months. However, all of the cases with secondary malignant parotid tumors were died due to malignancy. Complication ratio was 12% and facial paresis was the most common complication. Conclusion: Subtotal parotidectomy is an adequate and efficient surgical procedure for the benign parotid tumors and complication risk is considerably low when applied carefully. However it may be required complementary total parotidectomy for malignant tumors. The prognosis is very good especially for the primary malign parotid tumors. However, it is not satisfactory for the secondary malign tumors.Yayın Comparison of clinical outcomes of three different packing materials in the treatment of severe acute otitis externa(Cambridge University Press, 2018) Demir, Deniz; Yılmaz, Mahmut Sinan; Güven, Mehmet; Kara, Ahmet; Elden, Halil; Erkorkmaz, Ünal; Demir, DenizObjective To analyse the clinical outcomes of biodegradable synthetic polyurethane foam versus ribbon gauze and ear wick in the treatment of severe acute otitis externa. Methods Ninety-two adults with severe acute otitis externa were randomly assigned to groups receiving ear wick (n = 28), ribbon gauze (n = 34) or biodegradable synthetic polyurethane foam (n = 30). Clinical efficacy, in terms of otalgia, oedema, erythema and tenderness of the external auditory canal, was assessed before packing was applied and at follow up on the 3rd and 7th days of presentation. Results All packing materials were associated with improved otalgia and oedema on the 3rd day; however, there were significant differences between biodegradable synthetic polyurethane foam and the other packing materials, and there was no significant reduction in tenderness in the biodegradable synthetic polyurethane foam group on the 3rd day. In the ribbon gauze and ear wick groups, improvements in all clinical efficacy scores were statistically significant for all pairwise comparisons. Conclusion The three packing materials were all quite effective in treating severe acute otitis externa, but ear wick and ribbon gauze were superior to biodegradable synthetic polyurethane foam for relieving signs and symptoms, especially on the 3rd day.Yayın Comparison of the results of caloric and video head impulse tests in patients with Meniere's disease and vestibular migraine(Springerlink, 2021) Yılmaz, Mahmut Sinan; Kara, Ahmet; Güven, Mehmet; Demir, Deniz; Genç Elden, Sena; Eğilmez, Oğuz Kadir; Demir, DenizPurpose To compare the results of video head impulse test (vHIT) and caloric testing (CT) in patients with vestibular migraine (VM) and Ménière’s disease (MD) and to investigate the relationship between these two tests. Methods Patients with definite unilateral MD and VM were included in the study. All patients underwent both vHIT and CT. The vestibulo-ocular reflex (VOR) gains of lateral semicircular canals and saccadic waves in vHIT and the canal paresis factor for the CT were examined. Results CT was found abnormal in 39 (66.1%) patients with MD and in 17 (34%) patients with VM, while abnormal gain of the lateral canal was obtained in 23 MD (39%) patients and 9 (18%) VM patients. In all, 11.9% of patients with an abnormal vHIT had a normal CT, whereas 33.9% of those with an abnormal CT had a normal vHIT. Conclusion Loss of VOR detected by caloric testing is more common and severe in MD than VM. Although vHIT is useful and can give complementary information, vestibular testing with the caloric test still seems more sensitive for detecting hVOR pathology.Yayın Comparison of two different bone anchored hearing instruments: Baha-5 vs Ponto-plus(Taylor & Francis Online, 2019) Kara, Ahmet; Güven, Mehmet; Yılmaz, Mahmut Sinan; Demir, Deniz; Adigul, Çağlayan; Durgut, Merve; Elden, Halil; Mutlu, Fatih; İşeri, Mete; Demir, DenizBackground: To our knowledge, there is no study comparing Ponto Plus® (Oticon Medical AB, Askim, Sweden) and Baha® 5 (Cochlear Bone Anchored Solutions AG, Mölnlycke, Sweden) available in the literature. Aims/objectives: The primary aim was to compare the performance of the Baha 5 with the Ponto Plus device in terms of speech understanding in quiet and in noise. In addition, to determine statistically whether or not the difference between the abutment systems created any variation in terms of skin reaction. Materials and methods: Twenty bone-anchored hearing instrument users, ten in each group, were evaluated for speech understanding in quiet and several signal-to-noise ratios using the Turkish Matrix Test in a two-speaker setup. The Holger classifications were also reviewed to determine adverse skin reactions. Results: It was revealed that the hearing results of both devices were similar and, when the skin reactions were compared, there was no statistically significant difference between the two-implant systems. Conclusions and significance: Because of the similar results of the groups, it can be interpreted as the key different device features such as the size, weight, colour alternatives, and the ease of use of the devices might be important in terms of device preference.Yayın Comparison of ıncidence and severity of chronic postsurgical pain following ear surgery(Wolters Kluwer, 2018) Güven, Mehmet; Kara, Ahmet; Yılmaz, Mahmut Sinan; Demir, Deniz; Güven, Ebru Mihriban; Demir, DenizObjectives: Literature review shows a limited number of studies investigating chronic pain following ear surgeries. The effect of mastoidectomy on chronic postsurgical pain, however, has never been investigated. The present study investigates not only the incidence and severity of chronic pain following ear surgeries with and without mastoidectomy, but also predisposing diseases for pain. Patients and Methods: The study was performed in a total of 150 patients who underwent tympanoplasty or tympanomastoidectomy through a retroauricular incision in a single tertiary health care center. During the routine postoperative 3rd-month examination, the patients were questioned for the presence and severity of chronic pain, as well as the diseases that might predispose the pain. Results: The difference between the visual analog scale scores of the groups was not statistically significant. Comparison of pain character revealed that neuropathic pain is more prevalent in both the groups. Evaluating the relationship between concomitant diseases and chronic pain, it was observed that migraine, cervical pathology, and acute postsurgical pain were closely associated with chronic pain. Conclusion: It was demonstrated that mastoidectomy does not pose an additional risk for chronic postsurgical pain. However, patients with migraine, cervical pathology, and acute postsurgical pain are at risk for chronic postsurgical pain.Yayın Eritropoietin, hematocrit levels and red blood cell counts in pediatric obstructive sleep apnea(Anatomi Araştırmaları Derneği, 2019) Kara, Ahmet; Çelik, Bilgehan; Yılmaz, Mahmut Sinan; Demir, Deniz; Sayhan, Havva Kaplan; Güven, Mehmet; Demir, DenizObjective: We aimed to identify a biochemical marker which can be important for obstructive pathologies creating an important indication for adenotonsillectomy. Material and Methods: A total of 35 patients who had adenotonsillectomy operation with the diagnosis of obstructive adenotonsillar hypertrophy were compared with 35 control patients who had various surgeries for different reasons in terms of blood erythropoietin, hematocrit level and red blood cell count. Results: While mean of erythropoietin values of the study group was 9.46±4.2 mU/ml, this value was found to be 8.92±3.6 mU/ml in the control group. Hematocrit levels and erythrocyte counts of the patients in the study and control groups were very close to each other. It was seen that the differences were not statistically significant when the groups were compared via independent samples T-test. Conclusion and Significance: Even though it is not statistically significant, we believe that higher level of erythropoietin in the study group compared to the control group requires similar studies to be conducted on this subject with groups including larger number of patients and by creating sub-groups.Yayın Evaluation of incidence and prognosis of covid-19 in patients with nasal polyps(Sakarya University, 2022) İlhan, Necati; Demir, Deniz; Delibaş, Köksal; Güven, Mehmet; Yılmaz, Mahmut Sinan; Kara, Ahmet; Demir, DenizAmaç: Koronavirüs hastalığı 2019 (COVID-19), şiddetli akut solunum sendromu koronavirüs-2'nin (SARS-CoV-2) neden olduğu küresel bir pandemik bulaşıcı hastalıktır. IL -4, IL-5, IL-13 gibi tip 2 sitokinlerin ve eozionifililik enflamasyonun eşlik ettiği tip 2 immün yanıt nazal polipli kronik rinosinüzit (KRS+P) hastalarında COVID-19’a karşı potansiyel koruyucu etkisi olabilir. Bu çalışmada nazal polipli kronik rinosinüzit (KRS+P) hastalarında COVİD-19 sıklığı ve prognozu belirlemek amaçlandı. Materyal ve Metot: KRS+P nedeniyle ameliyat edilen 15 -65 yaş arası hastalar, insidans ve hastalık şiddeti açısından kontrol grubu ile karşılaştırıldı. Bulgular: KRS+P hastalarının %5,04'ünde Covid RTPCR testi pozitif çıktı. Kontrol grubunda bu oran %8,96 idi ve her iki grup arasındaki fark istatistiksel olarak anlamlıydı. İki grup hastalık şiddeti açısından karşılaştırıldığında anlamlı bir fark bulunmadı. Sonuç: KRS+P hastalarında COVID-19 insidansı daha düşüktü. Ancak nazal polip ile COVID-19 arasındaki ilişkiyi araştırmak için daha ileri prospektif çalışmalara ihtiyaç vardır.Yayın Evaluation of nasal tip shape in patients with severe caudal septal deviation after modified extracorporeal endonasal septoplasty(Elsevier, 2021) Demir, Deniz; Elden, Halil; Güven, Mehmet; Yılmaz, Mahmut Sinan; Kara, Ahmet; Demir, DenizObjectives The aim of this prospective study was to evaluate the effect of modified extracorporeal endonasal septoplasty on nasal tip shape and function in patients with severe caudal septal deviation. Methods The study population comprised of 55 patients undergoing modified extracorporeal endonasal septoplasty, which called marionette septoplasty. To analyse the aesthetic objective outcomes, postoperative photographs were measured for projection index (PI), tip projection (TP), nasolabial angle (NLA), tip deviation angle (TDA), nasofrontal angle (NFA), supratip height (STH), columellar height (CH), at three times (2 weeks, 3, and 6 months after surgery) and were compared with preoperative photographs. Functional and aesthetic outcomes were also evaluated using nasal obstruction symptom evaluation (NOSE) scale and standardized cosmesis and health nasal outcomes survey (SCHNOS). Results Between the pre- and post-operative 6th-month examinations, a significant increase in PI and TP were 7%, and 5% respectively. There was a significant alteration in the NLA and TDA values following the last examination (mean difference ± standard error of mean 9.68 ± 0.9° and 1.5 ± 0.8°, respectively). Moreover, the technique did not make a significant change in the final NFA, STH, and CH, measurements. Following surgery, the NOSE and SCHNOS scores were decreased significantly and the improvement continued over time until the last examination. Conclusion The present study findings suggest that the marionette septoplasty technique is an effective to correct and stabilize severe caudal septal deviations. This technique also can provide tip support and protection with a low incidence of dorsal irregularity.Yayın Evaluation of the effect of diclofenac sodium and 5-fluourasil in a 3d cholesteatoma cell culture model(Wolters Kluwer, 2019) Kara, Ahmet; Duman, Busra Oncel; Yazır, Yusufhan; Yılmaz, Mahmut Sinan; Unal Halbutogulları, Zehra Seda; Demir, Deniz; Öztaş Kara, Rabia; Bayraktar, Hakan; Guven, Mehmet; Demir, DenizIntroduction: Middle ear cholesteatoma is a benign disease with invasive and destructive clinical behaviors. It increases the rate of both chronic otitis media complications and revision surgeries. The most effective treatment of middle ear cholesteatoma is surgical excision, and there is no medical treatment for this disease. Exploring new medical treatment options may help to create treatment alternatives instead of surgery. Materials and Methods: Required cholesteatoma tissues for cell culture were excised from 4 different participants who underwent surgery in our clinic and agreed to give tissue for the study. Cholesteatoma-derived keratinocytes and fibroblasts were cocultured in temperature-sensitive culture dishes to make a three-dimensional (3D) cholesteatoma model. Then, the effects of 1% and 2% diclofenac sodium on viability and cell proliferation rates were examined using WST-1 and annexin-V tests. Results: Cell viability and proliferation rates were found to be lower and apoptosis rates were higher in the diclofenac sodium group versus the negative and positive control groups. Conclusion: In this present study, we described a new 3D cholesteatoma cell culture model developed using cell sheet technology and demonstrated the efficacy of diclofenac sodium on cholesteatoma for the first time in the literature. It may be used in patients with chronic otitis media with cholesteatoma, but further studies investigating ototoxic and neurotoxic effects of this molecule are needed.Yayın Hearing results according to ossiculoplasty techniques in chronic otitis media(Anatomi Araştırmaları Derneği, 2018) Kara, Ahmet; Yılmaz, Mahmut Sinan; Çelik, Bilgehan; Demir, Deniz; Güven, Mehmet; Demir, DenizIntroduction: In our study, it was aimed to analyze the postoperative hearing data of the patients with chronic otitis media who were operated with different ossiculoplasty techniques and to compare ossiculoplasty techniques with each other and the literature. Methods: Patients who were operated for chronic otitis media accompanied by hearing loss in Sakarya University Training and Research Hospital, Otorhinolaryngology Clinic between April 2013-December 2017 were retrospectively analyzed. Medical notes belonging to the patient were recorded. Thus, age, gender, surgical procedure and surgical findings of the disease, as well as the technique used for ossiculoplasty and audiometry test results at least 6 months postoperatively were determined. Findings: A total of 203 ossiculoplasty files scanned by the retrospective method were included in the study. Among these cases, data on 131 operated ears who had no graft failure and whose files were fully accessible were included in the study. Fifty-seven (57%) percent of the patients were female, and 56 (43%) were male. There was no statistically significant difference between the ossiculoplasty methods and the absence of stapes, high middle ear risk index and secondary surgeries were among the factors that reduce the success. Conclusion: As a result, we believe that it is important for the literature to demonstrate that open technique tympano-mastoidectomies can not be directly correlated with poor hearing outcomes and for the patients with intact manubrium mallei, audiological results of malleostapedopexy is as efficient as the patients implanted with partial ossicular replacement prosthesis (PORP).Yayın Hearing results according to ossiculoplasty techniques in chronic otitis media(Anatomi Araştırmaları Derneği, 2018) Kara, Ahmet; Yılmaz, Mahmut Sinan; Çelik, Bilgehan; Demir, Deniz; Güven, Mehmet; Demir, DenizIntroduction: In our study, it was aimed to analyze the postoperative hearing data of the patients with chronic otitis media who were operated with different ossiculoplasty techniques and to compare ossiculoplasty techniques with each other and the literature. Methods: Patients who were operated for chronic otitis media accompanied by hearing loss in Sakarya University Training and Research Hospital, Otorhinolaryngology Clinic between April 2013-December 2017 were retrospectively analyzed. Medical notes belonging to the patient were recorded. Thus, age, gender, surgical procedure and surgical findings of the disease, as well as the technique used for ossiculoplasty and audiometry test results at least 6 months postoperatively were determined. Findings: A total of 203 ossiculoplasty files scanned by the retrospective method were included in the study. Among these cases, data on 131 operated ears who had no graft failure and whose files were fully accessible were included in the study. Fifty-seven (57%) percent of the patients were female, and 56 (43%) were male. There was no statistically significant difference between the ossiculoplasty methods and the absence of stapes, high middle ear risk index and secondary surgeries were among the factors that reduce the success. Conclusion: As a result, we believe that it is important for the literature to demonstrate that open technique tympano-mastoidectomies can not be directly correlated with poor hearing outcomes and for the patients with intact manubrium mallei, audiological results of malleostapedopexy is as efficient as the patients implanted with partial ossicular replacement prosthesis (PORP).Yayın Impact of tonsillectomy on COVID–19 pandemic: an observational study of the incidence and prognosis(Taylor & Francis Online, 2021) Kara, Ahmet; Elden, Halil; Okur, Engin; Yılmaz, Mahmut Sinan; Mutlu, Fuldem; Güven, Mehmet; Demir, Deniz; Demir, DenizBackground Due to many different reasons such as possible coronavirus colonization in tonsillar tissue, decreased enzymatic antiviral activity, decreased cytokine activity from palatine tonsil tissue and reduced humoral and cellular immune response, tonsillectomy may alter the incidence of Covid–19. Aims/Objectives To reveal the frequency of Covid–19 in patients who underwent tonsillectomy and to analyze the effect of tonsillectomy on the severity of the disease. Materials and methods Patients aged between 15 and 65 and had a history of tonsillectomy were compared with control group in terms of incidence and severity of Covid–19 disease. Results A 4% Covid rRT–PCR test positivity rate was detected in patients with tonsillectomy whereas; it was 6.8% in the control group with a statistically significant difference. However, in terms of disease severity there was no difference between the two groups. Conclusions and significance It has been proven that tonsillectomy surgery does not pose an additional risk in terms of COVID 19 disease severity. The positive effect of tonsillectomy in terms of disease frequency has been even demonstrated for the first time in the literature.Yayın Intratympanic steroid treatment of bell’s palsy in patients with comorbid disease: a preliminary report(European Academy of Otology and Neurotology and the Politzer Society, 2020) Demir, Deniz; Genç, Sena; Güven, Mehmet; Yılmaz, Mahmut Sinan; Kara, Ahmet; Erkorkmaz, Ünal; Demir, DenizOBJECTIVES: This study evaluated the efficacy of intratympanic steroid injection (ITSI)as initial treatment and therecovery speed for Bell’s palsy (BP)inpatients with diabetes mellitus (DM)and/or hypertension (HT). MATERIALS AND METHODS: In total,90 patients with comorbid diseases diagnosed with BP received either ITSI (study group, n=61) or systemic steroid treatment (SST) (control group, n=29).The facial nerve function was assessed using the House–Brackmann (HB) grading system for up to 6 months or until complete recovery from BP. To investigate a relationship with the complete recovery time from BP, hematologic and baseline characteristic parameters were analyzed. RESULTS: The complete recovery rate of the ITSI and SST groups was 47.5% and 44.8% at the 1st month, 70.5% and 89.7% at the 3rd month, and 96.7% and 100% at the 6th month of the study, respectively. Lymphocyte and neutrophil values were significantly associated with the complete recovery time from BP. No major adverse events from ITSI itself were noticed during the procedure and during the follow-up of the treatment. CONCLUSION: Both treatment types have no superiorities over each other in initial treatment for BP in patients with comorbid diseases. ITSI is effective and safe and may avoid the unwanted side effects associated with systemic steroids inthese patients.Yayın Köy ve kentte yaşayan çocukların ve ailelerinin trafik konusundaki bilgi düzeylerinin karşılaştırılması(Maltepe Üniversitesi, 2019) Akgün, Ceren; Kara, AhmetAmaç: Son yıllarda ülkemizde yapılan araştırmalar, medyaya yansıyan haberler incelendiğinde trafik kazalarının her geçen gün arttığı, yaygın bir sorun haline geldiği gözlenmektedir. Trafik sorunlarını en aza indirebilmek küçük yaşlarda çocuklara verilen trafik eğitimi ile çocuklarda trafik bilinci oluşturabilmek, bunu alışkanlık ve yaşam tarzı olarak görebilmelerini sağlamakla mümkün görülmektedir. Bu noktadan hareketle araştırma, Afyonkarahisar il merkezindeki ve il merkezine bağlı ilçelerin köylerindeki anasınıflarına devam eden çocukların ve ailelerinin trafik konusundaki bilgi düzeylerinin karşılaştırılması amacıyla yapılmıştır.Yayın Paranazal sinüs bilgisayarlı tomografi incelemeleri ile keros sınıflaması ve kribriform plate derinliği asimetrisinin değerlendirilmesi(Sakarya Üniversitesi, 2018) Kara, Ahmet; Elden, Halil; Güven, Mehmet; Yılmaz, Mahmut Sinan; Demir, Deniz; Demir, DenizAmaç: Bu radyo-anatomik çalışma ile bölgemizdeki 18 yaş altı ve üstü populasyonun anterior kafa tabanı anatomisi ile ilgili veri elde etmek ve normatif verilerin elde edilmesi ile komplikasyon oranlarının azaltılması amaçlanmıştır. Gereç ve Yöntemler: Çalışmaya 7-18 yaş arası 100 kişi, 18-50 yaş arası 100 kişi olmak üzere toplam 200 kişi dahil edildi. Koronal planda çekilmiş bilgisayarlı tomografi görüntüleri dijital ortamda kemik pencerede incelendi. Olfaktor fossa derinlik ölçümleri yapıldı ve sonuçlar istatistiki yöntemler ile karşılaştırıldı. Bulgular: Pediatrik grubun yaş ortalaması 13.4±2.73 (erkek: 13.1±2.63, bayan: 13.6±2.82), erişkin grubun yaş ortalaması 39.9±7.46 (erkek: 40.6±7.82, bayan: 39.3±7.11) idi. Pediatrik ve erişkin grup lamina lateralis derinlikleri açısından karşılaştırıldığında aradaki fark istatistiki anlam oluşturmadı. Yine pediatrik ve erişkin gruplar kendi içlerinde cinsiyet farklılığı, sağ ve sol taraf asimerisi bakımından karşılaştırıldığında istatistiki anlamlı fark oluşmadı. Pediatrik grupta %15, erişkin grupta %18 oranında keros asimetrisi tespit edildi. Sonuç: Çalışmada gerçekleştirilen ölçümler sonucunda istatistiki olarak anlam ifade etmese de asimetrik keros vakaları konusunda cerrahın dikkatli olması gerekliliği literatür ile uyumlu bir şekilde tekrar vurgulanmıştır. Pediatrik yaş grubundaki farklılıklar için ise geniş katılımcı sayıları ile çalışmanın tekrarlanması önerilebilir
