Helvacioglu reproducibility index: a new algorithm to evaluate the effects of misalignments on the measurements of retinal nerve fiber layer by spectraldomain OCT

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dc.authorid0000-0002-7775-9053en_US
dc.contributor.authorHelvacıoğlu, Fırat
dc.contributor.authorUyar, Osman Murat
dc.contributor.authorTunç, Zeki
dc.contributor.authorKapran, Ziya
dc.date.accessioned2024-07-12T21:04:19Z
dc.date.available2024-07-12T21:04:19Z
dc.date.issued2015en_US
dc.departmentFakülteler, Tıp Fakültesien_US
dc.description.abstractAim: To evaluate the effect of misalignment on the measurements of retinal nerve fiber layer (RNFL) by spectral-domain optical coherence tomography (OCT). Methods: A total of 42 eyes from 21 healthy young subjects underwent RNFL measurements with RTVue spectral-domain OCT (Optovue Inc., Fremont, California, USA). Two baseline measurements with perfectly aligned central circle to the borders of the optic nerve and four misaligned measurements which were misaligned towards to four quadrants were taken. The differences in RNFL between the baseline and misaligned measurements were analyzed with a new algorithm called Helvacioglu reproducibility index (HRI) which is designed to measure the reproducibility of the scans by evaluating the RNFL changes in the four main quadrants. Results: The average RNFL scores of the first two baseline measurements have good correlation (c=0.930) and good reproducibility scores (0.15±0.07). Superior misaligned measurements had significantly lower superior quadrant score and higher inferior quadrant score, similar nasal and little higher temporal scores (P1, P2<0.001, P3=0.553, P4=0.001). Inferior misaligned measurements had significantly higher superior quadrant score and lower inferior quadrant score with similar temporal and little lower nasal scores (P1, P2<0.001, P3=0.315, P4=0.016). Nasal misaligned measurements had significantly higher temporal quadrant score and lower nasal quadrant score with little lower superior and inferior scores (P1, P2, P4<0.001, P3=0.005). Temporal misaligned measurements had significantly higher nasal quadrant score and lower temporal quadrant score with similar superior and little higher inferior scores (P1, P2<0.001, P3=0.943, P4=0.001). Conclusion: Good alignment of the central circle to the borders of optic nerve is crucial to have correct and repeatable RNFL measurements. Misalignment to a quadrant resulted in falsely low readings at that quadrant and falsely high readings at the opposite quadrant.en_US
dc.identifier.citationHelvacioglu, F., Uyar, O. M., Şencan, S., Tunc, Z. ve Kapran, Z. (2015). Helvacioglu reproducibility index: a new algorithm to evaluate the effects of misalignments on the measurements of retinal nerve fiber layer by spectral-domain OCT. International journal of ophthalmology, IJO Press. 8(5), s. 1008–1012.en_US
dc.identifier.doi10.3980/j.issn.2222-3959.2015.05.28
dc.identifier.endpage1012en_US
dc.identifier.issn2222-3959
dc.identifier.issn2227-4898
dc.identifier.issue5en_US
dc.identifier.pmid26558218en_US
dc.identifier.scopus2-s2.0-84944559327en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1008en_US
dc.identifier.urihttp://www.ijo.cn/gjyken/ch/reader/view_abstract.aspx?file_no=20150528&flag=1
dc.identifier.urihttps://doi.prg/10.3980/j.issn.2222-3959.2015.05.28
dc.identifier.urihttps://hdl.handle.net/20.500.12415/3774
dc.identifier.volume8en_US
dc.identifier.wosWOS:000361858600028en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorŞencan, Sadık
dc.language.isoenen_US
dc.publisherIJO Pressen_US
dc.relation.ispartofInternational Journal of Ophthalmologyen_US
dc.relation.publicationcategoryUluslararası Hakemli Dergide Makale - Kurum Öğretim Elemanıen_US
dc.rightsCC0 1.0 Universal*
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rights.urihttp://creativecommons.org/publicdomain/zero/1.0/*
dc.snmzKY01673
dc.subjectmisalignmenten_US
dc.subjectoptical coherence tomographyen_US
dc.subjectrepeatabilityen_US
dc.subjectreproducibilityen_US
dc.subjectretinal nerve fiber layeren_US
dc.titleHelvacioglu reproducibility index: a new algorithm to evaluate the effects of misalignments on the measurements of retinal nerve fiber layer by spectraldomain OCTen_US
dc.typeArticle
dspace.entity.typePublication

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