Anti-Müllerian hormone as a predictor of pregnancy in women under 35 years with unexplained infertility undergoing ICSI: a retrospective study

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dc.authorid0000-0002-4605-1167en_US
dc.authorid0000-0002-0717-1756en_US
dc.contributor.authorBayram, Hale
dc.contributor.authorDündar, Özgür
dc.contributor.authorDönmez Çakıl, Yaprak
dc.contributor.authorCıncık, Mehmet
dc.contributor.authorUyar, E. Elif
dc.date.accessioned2024-07-12T21:10:16Z
dc.date.available2024-07-12T21:10:16Z
dc.date.issued2021en_US
dc.departmentFakülteler, Tıp Fakültesien_US
dc.description.abstractBackground: Anti-Müllerian hormone (AMH) is a well-established marker for the determination of ovarian reserve. However, its role in the prediction of pregnancy is still under debate. In this retrospective study, we aimed to evaluate the relationship of serum AMH levels with pregnancy rates in patients with unexplained infertility undergoing ICSI. Moreover, we compared the predictive value of AMH with that of antral follicle count (AFC). Methods: Records of 76 patients under 35 years of age with AMH levels between 1 and 3.5 ng/mL were examined retrospectively. Participants were divided into groups based on their AMH level and age. Results: AMH levels in women under 30 years were found significantly higher than those in women over 30 years (P=0.033). Fifty-seven of 76 patients (75%) were pregnant. Age did not have a significant effect on the pregnancy rates in the selected study group (P=0.252). On the other hand, despite the poor predictive accuracy, serum AMH was shown to have a predictive value with a cut-off point of 1.95 ng/mL. Logistic regression tests demonstrated a higher pregnancy rate (3.396 fold) with an AMH level 1.95 or above. There was no significant relationship between AFC and pregnancy. Conclusions: AMH might have a role in the prediction of pregnancy after ICSI in patients under 35 years with unexplained infertility.en_US
dc.identifier.citationBayram, H., Dundar, O., Donmez Cakil, Y., Uyar, E. E. ve Cincik, M. (2022). Anti-Müllerian hormone as a predictor of pregnancy in women under 35 years with unexplained infertility undergoing ICSI: a retrospective study. Minerva Obstetrics and Gynecology, Minerva Medica. 74(2), s. 117-122.en_US
dc.identifier.doi10.23736/S2724-606X.21.04727-8
dc.identifier.endpage122en_US
dc.identifier.issn2724-6450
dc.identifier.issue2en_US
dc.identifier.pmid33904685en_US
dc.identifier.scopus2-s2.0-85128253424en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage117en_US
dc.identifier.urihttps://pubmed.ncbi.nlm.nih.gov/33904685/
dc.identifier.urihttps://doi.prg/10.23736/S2724-606X.21.04727-8
dc.identifier.urihttps://hdl.handle.net/20.500.12415/4227
dc.identifier.volume74en_US
dc.identifier.wosWOS:000799174600001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorCıncık, Mehmet
dc.language.isoenen_US
dc.publisherMinerva Medicaen_US
dc.relation.ispartofMinerva Obstetrics and Gynecologyen_US
dc.relation.publicationcategoryUluslararası Hakemli Dergide Makale - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKY02967
dc.subjectInfertilityen_US
dc.subjectIntracytoplasmic sperm injectionsen_US
dc.subjectPregnancyen_US
dc.subjectFertilizationen_US
dc.subjectAnti-Mullerian hormoneen_US
dc.titleAnti-Müllerian hormone as a predictor of pregnancy in women under 35 years with unexplained infertility undergoing ICSI: a retrospective studyen_US
dc.typeArticle
dspace.entity.typePublication

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