The comparison of del nido cardioplegia and crystalloid-based blood cardioplegia in adult isolated coronary bypass surgery: A randomized controlled trial

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dc.authorid0000-0001-7914-2201en_US
dc.contributor.authorDemir, Deniz
dc.contributor.authorBalcı, A.B.
dc.contributor.authorKahraman, Nail
dc.contributor.authorSünbül, S.A.
dc.contributor.authorGücü, A.
dc.contributor.authorSeker, I.B.
dc.contributor.authorBadem, Serdar
dc.contributor.authorYüksel, Ahmet
dc.contributor.authorÖzyazıcıoğlu, A.F.
dc.contributor.authorGöncü, M.T.
dc.contributor.authorDemir, Deniz
dc.date.accessioned2024-07-12T21:00:56Z
dc.date.available2024-07-12T21:00:56Z
dc.date.issued2022en_US
dc.departmentFakülteler, Tıp Fakültesien_US
dc.description.abstractBackground and Aim: In our study, patients who underwent isolated coronary artery bypass surgery (CABG) using Del Nido cardioplegia (DNC) and crystalloid-based cold blood cardioplegia (CBC) were compared. Subject and Methods: In this study, two groups of patients who underwent isolated CABG using DNC (n = 106) and CBC (n = 107) were prospectively randomized. Groups were compared in terms of many results such as troponin T, returning spontaneous rhythm, and cardioplegia volume. Results and Conclusions: Median troponin T levels of the DNC and CBC groups were compared for the 0th hour (baseline), 12th, 36th, and 60th hours. There was no statistical difference between groups in troponin T levels of the baseline 0th hour (18[33] vs. 22[27] pg/ml; P = 0.724). Troponin T levels at the 12th hour were less in the DNC group than the CBC group but no statistical difference between the groups (790[735] vs. 826[820] pg/ml; P = 0.068), respectively. Troponin T levels at 36th and 60th hours were higher in the CBC group compared to the DNC group, and a statistical difference was observed (580[546] vs. 650[550] pg/ml; P = 0.030) and (359[395] vs. 421[400] pg/ml; P = 0.020), respectively. After X-clamping, the spontaneous rhythm rate was statistically higher in the DNC group than the CBC group (72.60% vs. 37.40%; P < 0.001). There was no statistical difference between the groups in terms of postoperative arrhythmia, hospital stay, and mortality rates (P > 0.05). Based on data we acquired from the study, we think that DNC is at least as safe and effective as CBC in adult CABG cases.en_US
dc.identifier.citationDemir, D., Balcı, A.B., Kahraman, N., Sünbül, S.A. vd. (2022). The comparison of del nido cardioplegia and crystalloid-based blood cardioplegia in adult isolated coronary bypass surgery: A randomized controlled trial. Nigerian Journal of Clinical Practice, Wolters Kluwer. 25(12), s. 1998-2004.en_US
dc.identifier.endpage2004en_US
dc.identifier.issn1119-3077
dc.identifier.issue12en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1998en_US
dc.identifier.urihttps://www.njcponline.com/article.asp?issn=1119-3077;year=2022;volume=25;issue=12;spage=1998;epage=2004;aulast=Demir
dc.identifier.urihttps://hdl.handle.net/20.500.12415/3433
dc.identifier.volume25en_US
dc.institutionauthorDemir, Deniz
dc.language.isoenen_US
dc.publisherWolters Kluweren_US
dc.relation.ispartofNigerian Journal of Clinical Practiceen_US
dc.relation.isversionof10.4103/njcp.njcp_435_22en_US
dc.relation.publicationcategoryUluslararası Hakemli Dergide Makale - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKY03117
dc.subjectDel nido cardioplegiaen_US
dc.subjectisolated coronary artery bypassen_US
dc.subjectreturn spontaneous rhythmen_US
dc.titleThe comparison of del nido cardioplegia and crystalloid-based blood cardioplegia in adult isolated coronary bypass surgery: A randomized controlled trialen_US
dc.typeArticle
dspace.entity.typePublication

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