Epidemiological characteristics, clinical and laboratory findings supporting preliminary diagnosis of Crimean-Congo hemorrhagic fever in an endemic region in Turkey

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dc.authorid0000-0003-3799-1090en_US
dc.contributor.authorYeşilbağ, Zuhal
dc.contributor.authorKaradeniz, Aslı
dc.contributor.authorKoçulu, Safiye
dc.contributor.authorKayhan, Cahit Bekir
dc.date.accessioned2024-07-12T21:43:19Z
dc.date.available2024-07-12T21:43:19Z
dc.date.issued2020en_US
dc.departmentFakülteler, Tıp Fakültesien_US
dc.description.abstractBackground Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne disease that has various symptoms. Since rapid diagnosis is crucial for survival, understanding the characteristics of patients is important for clinicians while waiting for results. This study aimed to evaluate findings that support the preliminary diagnosis of suspected CCHF in patients and take a look at the management of CCHF in Turkey. Methods Demographics, presenting symptoms and laboratory findings of the patients admitted with a suspicion of CCHF, were recorded from the patient files and database of Ministry of Health. A diagnosis of CCHF was based on detection of immunoglobulin M (IgM) antibodies and/or viral RNA. The patients with and without CCHF were compared in terms of differences in epidemiological, clinical and laboratory findings. Results Out of 87 patients, 61 (70.1%) were CCHF and 26 (29.9%) were non-CCHF cases. Working with agriculture/livestock, tick exposure, contact with body fluids of animals, travel to rural areas within 2 weeks, fever, headache, leucopenia, anemia, international normalized ratio (INR) elevation were significantly more common in CCHF cases. According to multivariate analysis, tick exposure (odds ratio, OR 9.03, 95% confidence interval, CI 1.96–41.47, p?=?0.005), contact with body fluids of animals (OR 14.9, 95% CI 2.23–99.94, p?=?0.005), leucopenia (OR 13.65, 95% CI 2.55–72.91, p?=?0.02) and anemia (OR 8.41, 95% CI 1.06–66.42, p?=?0.04) were independently indicative for CCHF. Conclusion As it takes a considerable time for a definitive diagnosis, determining epidemiological features and risk factors is an important step for preliminary diagnosis of CCHF as well as early implementation of precautions against nosocomial transmission of the virus.en_US
dc.identifier.citationYeşilbağ, Z., Karadeniz, A., Koçulu, S. ve Kayhan, C. B. (2020). Epidemiological characteristics, clinical and laboratory findings supporting preliminary diagnosis of Crimean-Congo hemorrhagic fever in an endemic region in Turkey. Wiener klinische Wochenschrift, Springer.en_US
dc.identifier.doi10.1007/s00508-020-01719-5
dc.identifier.issn1613-7671
dc.identifier.pmid32749537en_US
dc.identifier.scopus2-s2.0-85089037799en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.urihttps://link.springer.com/article/10.1007/s00508-020-01719-5
dc.identifier.urihttps://doi.prg/10.1007/s00508-020-01719-5
dc.identifier.urihttps://hdl.handle.net/20.500.12415/7579
dc.identifier.wosWOS:000555707600001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofWiener klinische Wochenschriften_US
dc.relation.publicationcategoryUluslararası Hakemli Dergide Makale - Kurum Öğretim Elemanıen_US
dc.rightsCC0 1.0 Universal*
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rights.urihttp://creativecommons.org/publicdomain/zero/1.0/*
dc.snmzKY04025
dc.subjectCrimean-congo hemorrhagic feveren_US
dc.subjectEpidemiologyen_US
dc.subjectLeukopeniaen_US
dc.subjectRisk factorsen_US
dc.subjectTick exposureen_US
dc.titleEpidemiological characteristics, clinical and laboratory findings supporting preliminary diagnosis of Crimean-Congo hemorrhagic fever in an endemic region in Turkeyen_US
dc.typeArticle
dspace.entity.typePublication

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