Gençlerde sigara içiminin aterosklerotik risk faktörleri üzerine olumsuz etkisi
Küçük Resim Yok
Tarih
2009
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Gülhane Askeri Tıp Akademisi Halk Sağlığı AD.
Erişim Hakkı
CC0 1.0 Universal
info:eu-repo/semantics/openAccess
info:eu-repo/semantics/openAccess
Özet
AMAÇ: Sigaranın erişkin bireylerde önemli kardiyovasküler risk faktörü olduğu gösterilmiştir. Aterosklerozun erken yaşlarda başladığı gerçeğinden yola çıkarak bu çalışmada genç yaştaki bireylerde sigara içiminin aterosklerozu hızlandıran diğer risk faktörleri üzerine etkisini ortaya koymayı amaçladık. YÖNTEM: Çalışmaya 164 genç birey (21,14±2,06) dahil edildi. Bireyler sigarayı kullanma sıklığına göre; hiç içmeyen (n=48), bırakmış (n=30), günde 1-3 adet (n=26), günde yarım paket (n=26) ve günde bir paket kullanan (n=34) şeklinde gruplandırıldı. Bireylerin vücut kitle indeksleri (VKI) hesaplandı. Sistolik ve diyastolik kan basıncı (SKB, DKB) ölçümleri yapıldı. Logic 5 Pro Renkli doppler cihazıyla karotid-intima media kalınlığı (KIMK) ölçümleri yapıldı. 12 saatlik açlık serum örneklerinden toplam kolesterol, LDL, HDL kolesterol düzeyleri ile trigliserid düzeyleri ölçüldü. İstatiski analizler One way ANOVA testi ile SPSS 11.0 kullanılarak yapıldı BULGULAR: Gruplar arasında VKI, SKB, DKB açısından anlamlı fark izlenmemiştir. Günde bir paket sigara içen grupta HDL kolesterol düzeyi anlamlı derecede azalmış, LDL kolesterol düzeyi de anlamlı derecede artmış olarak bulundu. Karotis intima mediya kalınlığı ise günde 1 paket içenlerde artmış ancak sonuç istatistiki anlamlı düzeye ulaşmamıştır. Aynı grupta trigliserid düzeyleri ise azalmış olarak izlenmiştir. SONUÇ: Sigara içimi özellikle genç yaşlardan itibaran aterosklerotik risk faktörlerini olumsuz yönde etkilemektedir. Dolayısı ile kalp ve damar hastalıkları prevalansını azaltmak için genç yaşlardan itibaren sigara faktörünün ortadan kaldırılması gerekmektedir.
AIM: It was documented that smoking was a significant atherosclerotic risk factor for adults. However reality of the initiation of atherosclerosis at childhood guided us to evaluate the probable effects of smoking on other atherosclerotic risk factors at young ages. METHODS: One hundred sixty four young subjects (age 21.14± 2.06) were enrolled. Participants were grouped as not smoking (n=48), ex-smoking (n=30), 1-3 cigarettes/day (n=26), a half package/day (n=26), a package/day (n=34). Body mass index (BMI) of subjects were calculated. Systolic and diastolic blood pressures (SBP, DBP) were measured. Carotid intima media thickness (IMT) was measured by Logic5 pro Colour Doppler Device. Total cholesterol, LDL cholesterol, HDL cholesterol, and triglyceride levels of subjects were measured from the serum obtained at 12 hour fasting state. IMT and IVSd were measured by transverse and 3S probes using. Statistical analysis was performed by One-way ANOVA test using SPSS 11.0 for Windows. RESULTS: BMI, SBP, and DBP were not different between groups (p=0.16). HDL cholesterol was significantly lowered whereas LDL cholesterol was significantly increased in group smoking one package/day. Also carotid IMT was increased in patients smoking one package/day compared to others but data was not statistically significant. Triglyceride level group. CONCLUSION: Smoking effects atherosclerotic risk factors unfavorably even at young ages. Thus smoking should be eradicated since earlier ages in order to reduce the prevalence of cardiovascular diseases.
AIM: It was documented that smoking was a significant atherosclerotic risk factor for adults. However reality of the initiation of atherosclerosis at childhood guided us to evaluate the probable effects of smoking on other atherosclerotic risk factors at young ages. METHODS: One hundred sixty four young subjects (age 21.14± 2.06) were enrolled. Participants were grouped as not smoking (n=48), ex-smoking (n=30), 1-3 cigarettes/day (n=26), a half package/day (n=26), a package/day (n=34). Body mass index (BMI) of subjects were calculated. Systolic and diastolic blood pressures (SBP, DBP) were measured. Carotid intima media thickness (IMT) was measured by Logic5 pro Colour Doppler Device. Total cholesterol, LDL cholesterol, HDL cholesterol, and triglyceride levels of subjects were measured from the serum obtained at 12 hour fasting state. IMT and IVSd were measured by transverse and 3S probes using. Statistical analysis was performed by One-way ANOVA test using SPSS 11.0 for Windows. RESULTS: BMI, SBP, and DBP were not different between groups (p=0.16). HDL cholesterol was significantly lowered whereas LDL cholesterol was significantly increased in group smoking one package/day. Also carotid IMT was increased in patients smoking one package/day compared to others but data was not statistically significant. Triglyceride level group. CONCLUSION: Smoking effects atherosclerotic risk factors unfavorably even at young ages. Thus smoking should be eradicated since earlier ages in order to reduce the prevalence of cardiovascular diseases.
Açıklama
Anahtar Kelimeler
Ateroskleroz, sigara, genç, carotis intima mediya kalınlığı, kolesterol, Atherosclerosis, smoking, young, carotis intima media thickness, cholesterol
Kaynak
TAF Preventive Medicine Bulletin
WoS Q Değeri
Scopus Q Değeri
Cilt
8
Sayı
3
Künye
Aparcı, M., Arslan, Z., Işılak, Z., Kardeşoğlu, E., Yiğiner, Ö., Uz, Ö., Çelik, T., İyisoy, A., Cingözbay, B.Y. ve Cebeci, B.S. (2009). Gençlerde sigara içiminin aterosklerotik risk faktörleri üzerine olumsuz etkisi / Unfavorable effects of smoking on atherosclerotic risk factors of young individuals. TAF Preventive Medicine Bulletin, Gülhane Askeri Tıp Akademisi Halk Sağlığı AD.. 8(3), s. 193-198.
