Initial experience of 3 tesla apparent diffusion coefficient values in differentiating benign and malignant thyroid nodules

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dc.authorid0000-0003-4462-5953en_US
dc.contributor.authorIlica, A. Turan
dc.contributor.authorArtas, Hakan
dc.contributor.authorAyan, Asli
dc.contributor.authorGunal, Armagan
dc.contributor.authorEmer, Ozdes
dc.contributor.authorKilbas, Zafer
dc.contributor.authorMeric, Coskun
dc.contributor.authorAtasoy, Mehmet Mahir
dc.contributor.authorUzuner, Ovsev
dc.date.accessioned2024-07-12T21:50:52Z
dc.date.available2024-07-12T21:50:52Z
dc.date.issued2013en_US
dc.departmentMaltepe Üniversitesien_US
dc.description.abstractPurpose: To evaluate the role of diffusion-weighted magnetic resonance imaging (DWMRI) in differentiating benign and malignant thyroid nodules using a 3 Tesla (T) MRI scanner. Materials and Methods: Twenty-eight nodules in 25 patients and 14 healthy control cases were included in the study. DWMRI was acquired with 6 b values with a 3T MRI scanner. The apparent diffusion coefficient (ADC) values of the nodules were calculated from reconstructed ADC map images and were compared with the final histopathological diagnoses. Results: The mean ADC value of the benign nodules was 1548 +/- 353.4 (x106 mm2/s), and the mean ADC of the malignant nodules was 814 +/- 177.12 (x106 mm2/s). The normal thyroid tissue had a mean ADC value of 1323.43 +/- 210.35 x 106 mm2/s (9581689 x 106 mm2/s) in the healthy control group. The ADC values were significantly different among the three groups (P = 0.001). An ADC value of 905 x 106 mm2/s was determined to be the cutoff value for differentiating benign and malignant nodules, with 90% (55.598.3) sensitivity and 100% (81.3100.0) specificity. Conclusion: This study suggests that the ADC values of nodules measured with a 3T MRI scanner could help in differentiating benign thyroid nodules from malignant nodules. J. Magn. Reson. Imaging 2013;37:10771082. (c) 2012 Wiley Periodicals, Inc.en_US
dc.identifier.doi10.1002/jmri.23913
dc.identifier.endpage1082en_US
dc.identifier.issn1053-1807
dc.identifier.issn1522-2586
dc.identifier.issue5en_US
dc.identifier.pmid23148044en_US
dc.identifier.scopus2-s2.0-84876466791en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1077en_US
dc.identifier.urihttps://dx.doi.org/10.1002/jmri.23913
dc.identifier.urihttps://hdl.handle.net/20.500.12415/8216
dc.identifier.volume37en_US
dc.identifier.wosWOS:000318049200007en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherWILEYen_US
dc.relation.ispartofJOURNAL OF MAGNETIC RESONANCE IMAGINGen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKY01954
dc.subjectthyroiden_US
dc.subjectnodular diseaseen_US
dc.subjectdiffusion-weighted MRIen_US
dc.titleInitial experience of 3 tesla apparent diffusion coefficient values in differentiating benign and malignant thyroid nodulesen_US
dc.typeArticle
dspace.entity.typePublication

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