Gallstones and Concomitant Gastric Helicobacter pylori Infection

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dc.contributor.authorAttaallah, Wafi
dc.contributor.authorYener, Nese
dc.contributor.authorUgurlu, M. Umit
dc.contributor.authorManukyan, Manuk Norayık
dc.contributor.authorAsmaz, Ebru
dc.contributor.authorAktan, A. Ozdemir
dc.date.accessioned2024-07-12T21:47:06Z
dc.date.available2024-07-12T21:47:06Z
dc.date.issued2013en_US
dc.departmentMaltepe Üniversitesien_US
dc.description.abstractBackground. The association of gallstones with Helicobacter pylori has been investigated but not clearly demonstrated. In this study, the presence of H. pylori in the gallbladder mucosa of patients with symptomatic gallstones was investigated. Method. Ninety-four consecutive patients with symptomatic gallstone disease were enrolled for the study. Gastroscopy and gastric H. pylori urease test were done before cholecystectomy to all patients who accepted. After cholecystectomy, the gallbladder tissue was investigated in terms of H. pylori by urease test, Giemsa, and immunohistochemical stain. Results. Overall 35 patients (37%) gallbladder mucosa tested positive for H. pylori with any of the three tests. Correlation of the three tests Giemsa, IHC, and rapid urease test was significant (r(s): 0590, P > 0.001). Rapid urease test was positive in the gastricmucosa in 47 (58.7%) patients, and it was positive in the gallbladder mucosa in 21 patients (22%). In 15 patients both gastric and gallbladder tested positive with the urease test. There was significant correlation of rapid urease test in both of gallbladder and gastric mucosa (P = 0.0001). Conclusion. Study demonstrates the presence of H. pylori in the gallbladders of 37% of patients with symptomatic gallstones.en_US
dc.identifier.doi10.1155/2013/643109
dc.identifier.issn1687-6121
dc.identifier.issn1687-630X
dc.identifier.pmid23762037en_US
dc.identifier.scopus2-s2.0-84878738026en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.urihttps://dx.doi.org/10.1155/2013/643109
dc.identifier.urihttps://hdl.handle.net/20.500.12415/8007
dc.identifier.wosWOS:000319923300001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherHINDAWI LTDen_US
dc.relation.ispartofGASTROENTEROLOGY RESEARCH AND PRACTICEen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKY01064
dc.titleGallstones and Concomitant Gastric Helicobacter pylori Infectionen_US
dc.typeArticle
dspace.entity.typePublication

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