Asymmetric Dimethylarginine and Its Relation As a Biomarker in Nephrologic Diseases

dc.contributor.authorSitar, Mustafa E.
dc.date.accessioned2024-07-12T21:45:13Z
dc.date.available2024-07-12T21:45:13Z
dc.date.issued2016en_US
dc.departmentMaltepe Üniversitesien_US
dc.description.abstractIt is encouraging to observe that a search for publications on "asymmetric dimethylarginine (ADMA)" in PubMed, as updated on June 2016, yielded >2500 items, 24 years after a splendid paper published by Vallance et al in which the authors proposed that ADMA accumulation could be a cardiovascular risk factor in chronic kidney diseases. ADMA is the endogenous inhibitor of nitric oxide synthase and is related to endothelial dysfunction, which plays an important role in vascular damage elicited by various cardiometabolic risk factors. Although current knowledge suggests that ADMA has critical central roles in renal diseases, there are still unexplained details. The present article aims to provide a review on ADMA and its relation as a biomarker in nephrologic diseases. We aimed to systematize articles in which ADMA levels were assessed in order to clarify its role in many diseases and establish its reference values in different populations.en_US
dc.identifier.doi10.4137/BMIMI.S38434
dc.identifier.endpage137en_US
dc.identifier.issn1177-2719
dc.identifier.pmid27980388en_US
dc.identifier.scopus2-s2.0-85012882394en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage131en_US
dc.identifier.urihttps://dx.doi.org/10.4137/BMIMI.S38434
dc.identifier.urihttps://hdl.handle.net/20.500.12415/7812
dc.identifier.volume11en_US
dc.identifier.wosWOS:000389333400001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorSitar, Mustafa E.
dc.language.isoenen_US
dc.publisherSAGE PUBLICATIONS LTDen_US
dc.relation.ispartofBIOMARKER INSIGHTSen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKY00415
dc.subjectasymmetric dimethylarginineen_US
dc.subjectbiomarkeren_US
dc.subjectendothelial dysfunctionen_US
dc.subjectnitric oxideen_US
dc.subjectoxidative stressen_US
dc.subjectrenal failureen_US
dc.titleAsymmetric Dimethylarginine and Its Relation As a Biomarker in Nephrologic Diseasesen_US
dc.typeArticle
dspace.entity.typePublication

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