Relation of maternal vitamin D status with gestational diabetes mellitus and perinatal outcome

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dc.authorid0000-0001-5472-7465en_US
dc.contributor.authorNiyazoğlu, Mutlu
dc.contributor.authorHatipoğlu, Esra
dc.contributor.authorAydoğan, Begüm
dc.contributor.authorDellal, Fatma Dilek
dc.contributor.authorYavuz, Arzu
dc.contributor.authorHacıoğlu, Yalçın
dc.contributor.authorKaya, Fatih Öner
dc.contributor.authorKumru, Selahattin
dc.date.accessioned2024-07-12T21:01:22Z
dc.date.available2024-07-12T21:01:22Z
dc.date.issued2015en_US
dc.departmentFakülteler, Tıp Fakültesien_US
dc.description.abstractObjective To investigate the relationship between maternal vitamin D status and glucose intolerance, and its impact on pregnant women and their newborns. Methods A cohort of pregnant women were divided into three groups: women with gestational diabetes mellitus, ones with normal results both after the 50 gr and 100 gr OGTT (CG-1) and ones having a positive result after the 50 gr OGTT screening but negative results for gestational diabetes mellitus (GDM) after the 100 gr OGTT (CG-2) Results The newborn length in CG-1 was greater than in GDM and CG-2 (p= 0.002 and p= 0.02). Fasting blood glucose and insulin resistance (IR) were negatively correlated with length of the newborns (r=?0.3, p=0.03 and r=?0.3, p=0.01). The newborns of women with GDM had lower APGAR-1 and 5 scores than those of CG-1 and CG-2 (APGAR-1 p= 0.001 and p= 0.004, APGAR-5 p=0.005 and p=0.007, respectively). APGAR scores were correlated negatively with IR (APGAR-1 r=?0.32, p=0.01, APGAR-5 r=?0.3, p=0.03) and positively with 25OHD levels (APGAR-1 r=0.3, p=0.01, APGAR-5 r=0.3, p=0.02). Conclusion Vitamin D deficiency, gestational diabetes and insulin resistance are interrelated. Severe vitamin D deficiency during pregnancy is associated with poor pregnancy and neonatal outcome.en_US
dc.identifier.citationNiyazoğlu, M., Hatipoğlu, E., Aydoğan, B. vd. (2015). Relation of maternal vitamin D status with gestational diabetes mellitus and perinatal outcome. Afr Health Sci., Pubmed. 15(2), s. 523-531.en_US
dc.identifier.endpage531en_US
dc.identifier.issue2en_US
dc.identifier.startpage523en_US
dc.identifier.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480463/
dc.identifier.urihttps://hdl.handle.net/20.500.12415/3496
dc.identifier.volume15en_US
dc.institutionauthorKaya, Fatih Öner
dc.language.isoenen_US
dc.publisherPubmeden_US
dc.relation.ispartofAfr Health Scien_US
dc.relation.isversionof10.4314/ahs.v15i2.27en_US
dc.relation.publicationcategoryUluslararası Hakemli Dergide Makale - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKY00121
dc.subjectVitamin D deficiencyen_US
dc.subjectgestational diabetesen_US
dc.subjectinsulin resistanceen_US
dc.subjectpregnancy and neonatal outcomeen_US
dc.titleRelation of maternal vitamin D status with gestational diabetes mellitus and perinatal outcomeen_US
dc.typeArticle
dspace.entity.typePublication

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