A randomized study comparing cyclophosphamide, doxorubicin, vincristine (CAV) with cyclophosphamide, etoposide, vincristine, methotrexate (CEVM) in patients with small cell lung cancer

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dc.authorid0000-0002-8335-1927en_US
dc.contributor.authorErkişi, Melek
dc.contributor.authorÜnsal, Mustafa
dc.contributor.authorTunalı, C.
dc.contributor.authorDoran, F.
dc.date.accessioned2024-07-12T21:04:38Z
dc.date.available2024-07-12T21:04:38Z
dc.date.issued1993en_US
dc.departmentFakülteler, Tıp Fakültesien_US
dc.description.abstractThis trial was carried out to assess the response rate and survival benefit achieved, if any, by substitution of etoposide for doxorubicin and addition of methotrexate in combination with cyclophosphamide and vincristine in the treatment of 113 patients with small cell lung carcinoma (SCLC). Cyclophosphamide, etoposide, vincristine, methotrexate (CEV-M) yielded a response rate of 75% in localized disease (LD) and 63% in extensive disease (ED), versus 61% in LD and 52% in ED in the cyclophosphamide, doxorubicin, vincristine (CAV) arm. There was also a significant survival benefit for the respondera in favor of CEV-M (21.7±3.8 months of median survival compared to 13.6±2.8 months in CAV arm) in patients with LD.en_US
dc.identifier.citationErkişi, M., Ünsal, M., Tınalı, C. ve Doran, F. (1994). A randomized study comparing cyclophosphamide, doxorubicin, vincristine (CAV) with cyclophosphamide, etoposide, vincristine, methotrexate (CEVM) in patients with small cell lung cancer. Journal of Chemotherapy. 5(1), s. 56-59.en_US
dc.identifier.endpage59en_US
dc.identifier.issue1en_US
dc.identifier.startpage56en_US
dc.identifier.urihttps://www.tandfonline.com/doi/abs/10.1080/1120009X.1993.11739211?journalCode=yjoc20
dc.identifier.urihttps://hdl.handle.net/20.500.12415/3800
dc.identifier.volume5en_US
dc.institutionauthorBurgut, Hüseyin Refik
dc.language.isoenen_US
dc.publisherTaylor and Francis Onlineen_US
dc.relation.ispartofJournal of Chemotherapyen_US
dc.relation.isversionof10.1080/1120009X.1993.11739211en_US
dc.relation.publicationcategoryUluslararası Hakemli Dergide Makale - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKY01829
dc.subjectChemotherapyen_US
dc.subjectCell lung canceren_US
dc.subjectEtoposideen_US
dc.titleA randomized study comparing cyclophosphamide, doxorubicin, vincristine (CAV) with cyclophosphamide, etoposide, vincristine, methotrexate (CEVM) in patients with small cell lung canceren_US
dc.typeArticle
dspace.entity.typePublication

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