Diagnostic algorithm in patients with superior vena cava syndrome and efficacy of cervical mediastinoscopy

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dc.authorid0000-0001-9169-560Xen_US
dc.contributor.authorAlpay, Levent
dc.contributor.authorLaçin, Tunç
dc.contributor.authorKoşar, Altuğ
dc.contributor.authorMısırlıoğlu, A. K.
dc.contributor.authorÖztaş, S.
dc.contributor.authorCoşkun, T.
dc.contributor.authorBaysungur, V.
dc.contributor.authorYalçınkaya, I.
dc.date.accessioned2024-07-12T21:01:11Z
dc.date.available2024-07-12T21:01:11Z
dc.date.issued2014en_US
dc.departmentFakülteler, Tıp Fakültesien_US
dc.description.abstractBackground : Superior vena cava syndrome (SVCS) is the result of the direct obstruction of the superior vena cava by malignancy and/or mediastinal lymphadenopathy. Our aim is to propose a diagnostic algorithm for undiagnosed superior vena cava syndrome patients and compare the diagnostic value, mortality and morbidity rates in patients diagnosed by mediastinoscopy. Methods : Ninety-seven patients with SVCS underwent diagnostic management starting with the least invasive technique and proceeding to more advanced and invasive methods between January 2000 and June 2013. Seventy one (73%) patients received histopathologic diagnosis using local biopsy, endobronchial biopsy by fiberoptic bronchoscopy and/or endobronchial ultrasound (EBUS) and CT-guided fine needle aspiration biopsy. Twenty six patients out of 97 patients who had superior vena cava syndrome underwent cervical mediastinoscopy for definitive diagnosis. Four patients (three male and one female) received histopathologic diagnosis using EBUS with the use of this method in our institution after 2010. Results : Of 26 patients who underwent cervical mediastinoscopy, 11 had small cell lung carcinoma, six had squamous cell lung carcinoma, three had adenocarcinoma, two had lymphoma, one had thymoma, one had tuberculosis, one had seminoma and one had chronic fibrous mediastinitis. Definitive tissue diagnosis was obtained in all patients. No perioperative mortality was recorded. One patient had minor bleeding which was controlled without additional surgical intervention. Conclusions : We propose a diagnostic algorithm in undiagnosed patients with superior vena cava syndrome. We conclude that cervical mediastinoscopy is a safe, fast and effective technique to establish pathologic diagnosis, and directs the physicians to apply the appropriate treatment in clinically diagnosed superior vena cava syndrome when less invasive techniques have been unsuccessful.en_US
dc.identifier.citationAlpay, L., Laçin, T., Koşar, A., Mısırlıoğlu, A. K., Öztaş, S., Coşgun, T., Baysungur, V. ve Yalçınkaya. I. (2014). Diagnostic Algorithm in Patients with Superior Vena Cava Syndrome and Efficacy of Cervical Mediastinoscopy. Acta Chirurgica Belgica. 114, s. 309-312.en_US
dc.identifier.endpage312en_US
dc.identifier.issn0001-5458
dc.identifier.issue114en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage309en_US
dc.identifier.urihttps://www.tandfonline.com/doi/abs/10.1080/00015458.2014.11681033
dc.identifier.urihttps://hdl.handle.net/20.500.12415/3466
dc.institutionauthorKoşar, Altuğ
dc.language.isoenen_US
dc.publisherRoyal Belgian Society for Surgeryen_US
dc.relation.ispartofActa Chirurgica Belgicaen_US
dc.relation.publicationcategoryUluslararası Hakemli Dergide Makale - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKY00032
dc.titleDiagnostic algorithm in patients with superior vena cava syndrome and efficacy of cervical mediastinoscopyen_US
dc.typeArticle
dspace.entity.typePublication

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