Effects of Hyperandrogenism on Tear Function and Tear Drainage in Patients with Polycystic Ovary Syndrome

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dc.authorid0000-0002-3166-9052en_US
dc.contributor.authorCoksuer, Hakan
dc.contributor.authorOzcura, Fatih
dc.contributor.authorOghan, Fatih
dc.contributor.authorHaliloglu, Berna
dc.contributor.authorKaratas, Serap
dc.date.accessioned2024-07-12T21:51:28Z
dc.date.available2024-07-12T21:51:28Z
dc.date.issued2011en_US
dc.departmentMaltepe Üniversitesien_US
dc.description.abstractOBJECTIVE: Polycys tic ovary syndrome (PCOS) is an endocrinopathy characterized by chronic anovulation and hyperandrogenism. Hormonal changes can affect ocular surface and tear functions. We evaluated dry eye symptoms, clinical tear film alterations, and tear clearance in patients with PCOS. STUDY DESIGN: Thirty-five women with PCOS and 22 healthy individuals were enrolled in the study. An ocular surface disease index (OSDI) questionnaire was administered, and after the routine ophthalmologic examination tear film breakup time (TB UT) and Schirmer tests were performed. Tear clearance was assessed via fluorescein dye disappearance test (FDDT). RESULTS: No difference was observed in Schirmer test between the groups, however OSDI scores were significantly higher (p=0.01) and TBUT was significantly lower (p=0.01) in PCOS patients than in the control women. FDDTs were not different between the PCOS and control subjects. CONCLUSION: Our findings suggest that patients diagnosed with PCOS should be advised to obtain an ophthalmic examination, especially for dry eye. (J Reprod Med 2011;56:65-70)en_US
dc.identifier.endpage70en_US
dc.identifier.issn0024-7758
dc.identifier.issue01.Feben_US
dc.identifier.pmid21366130en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage65en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12415/8266
dc.identifier.volume56en_US
dc.identifier.wosWOS:000287114600012en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSCI PRINTERS & PUBL INCen_US
dc.relation.ispartofJOURNAL OF REPRODUCTIVE MEDICINEen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKY02037
dc.subjectocular surface disease indexen_US
dc.subjectpolycystic ovary syndromeen_US
dc.subjectSchirmer testen_US
dc.subjecttear film breakup timeen_US
dc.subjecttearsen_US
dc.titleEffects of Hyperandrogenism on Tear Function and Tear Drainage in Patients with Polycystic Ovary Syndromeen_US
dc.typeArticle
dspace.entity.typePublication

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