Successful treatment of massive pulmonary embolism in a pregnant woman, with low-dose, slow infusion of tissue plasminogen activator

Basit Öğe Kaydı
dc.contributor.authorBiteker, Murat
dc.contributor.authorEkşi Duran, Nilüfer
dc.contributor.authorÖzkan, Mehmet
dc.date.accessioned2024-07-12T21:12:25Z
dc.date.available2024-07-12T21:12:25Z
dc.date.issued2010en_US
dc.departmentFakülteler, Tıp Fakültesien_US
dc.description.abstractPulmonary embolism (PE) is an important cause of morbidity and mortality during pregnancy. A 21-year-old pregnant woman presented with chest pain and progressive shortness of breath at 35 weeks of gestation. Her respiratory rate was 26 breaths/min. Electrocardiography showed sinus tachycardia and nonspecific ST-T changes. Her plasma D-dimer level was elevated (1,325 ng/ml). Transthoracic echocardiography revealed enlargement of the right ventricle and a large, highly mobile thrombus in the right atrium moving during diastole into the right ventricle. Doppler ultrasonography of the lower extremities showed bilateral acute deep femoral vein thrombosis. Following the diagnosis of right heart thrombosis with massive PE, low-dose and prolonged infusion of tissue-type plasminogen activator (25 mg in three hours) was administered. Echocardiography performed six hours after thrombolysis showed a significant decrease in the right ventricular size and complete lysis of the thrombus in the right heart. Thrombosis risk panel studies showed factor V Leiden homozygote mutation. A live newborn was delivered by cesarean section at 37 weeks of gestation. No complications were seen during a 6-month follow-up.en_US
dc.identifier.citationBiteker, M., Ekşi Duran, N. ve Özkan, M. (2010). Successful treatment of massive pulmonary embolism in a pregnant woman, with low-dose, slow infusion of tissue plasminogen activator. Türk Kardiyoloji Derneği Arşivi. 38(1), s. 32-34.en_US
dc.identifier.endpage34en_US
dc.identifier.issue1en_US
dc.identifier.startpage32en_US
dc.identifier.urihttps://archivestsc.com/tr/
dc.identifier.urihttps://hdl.handle.net/20.500.12415/4480
dc.identifier.volume38en_US
dc.institutionauthorEkşi Duran, Nilüfer
dc.language.isoenen_US
dc.publisherTürk Kardiyoloji Derneğien_US
dc.relation.ispartofTürk Kardiyoloji Derneği Arşivien_US
dc.relation.publicationcategoryUlusal Hakemli Dergide Makale - Kurum Öğretim Elemanıen_US
dc.rightsCC0 1.0 Universal*
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rights.urihttp://creativecommons.org/publicdomain/zero/1.0/*
dc.snmzKY03827
dc.subjectPregnancy complicationsen_US
dc.subjectCardiovascularen_US
dc.subjectPulmonary embolism/drug therapyen_US
dc.subjectThrombolytic therapyen_US
dc.subjectTissue plasminogen activator/therapeutic useen_US
dc.titleSuccessful treatment of massive pulmonary embolism in a pregnant woman, with low-dose, slow infusion of tissue plasminogen activatoren_US
dc.typeArticle
dspace.entity.typePublication

Dosyalar

Koleksiyon

Tıp Fakültesi Koleksiyonu