Investigation of human papillomavirus DNA in colorectal carcinomas and adenomas

Basit Öğe Kaydı
dc.authorid0000-0001-7344-5826en_US
dc.contributor.authorYavuzer, Dilek
dc.contributor.authorKaradayi, Nimet
dc.contributor.authorSalepci, Taflan
dc.contributor.authorBaloglu, Huseyin
dc.contributor.authorDabak, Resat
dc.contributor.authorBayramicli, Oya Uygur
dc.date.accessioned2024-07-12T21:51:57Z
dc.date.available2024-07-12T21:51:57Z
dc.date.issued2011en_US
dc.departmentMaltepe Üniversitesien_US
dc.description.abstractHuman papillomavirus (HPV) has been considered to be an etiological agent for anogenital cancers, such as cervical cancer and possibly a subset of cancers of the aerodigestive tract. The aim of the study was to evaluate the presence of human papillomavirus DNA in colorectal carcinomas and adenomas. Formalin-fixed and paraffin-embedded archival tissue samples were used for DNA extraction. One hundred and six colorectal carcinomas and 62 adenomas were screened by nested polymerase chain reaction (PCR) for HPV DNA with a control group of 49 cervical tissues with invasive cervical carcinoma and cervical intraepithelial neoplasia (CIN). In the study group, we did not find HPV DNA positivity in any of all the colorectal carcinomas and adenomas. In the control group with cervical lesions, 34 out of 49 (69.4%) samples were positive for the HPV DNA. These results indicated that there was no correlation between HPV infection and colorectal carcinomas and adenomas.en_US
dc.identifier.doi10.1007/s12032-010-9416-4
dc.identifier.endpage132en_US
dc.identifier.issn1357-0560
dc.identifier.issn1559-131X
dc.identifier.issue1en_US
dc.identifier.pmid20082157en_US
dc.identifier.scopus2-s2.0-79952251587en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage127en_US
dc.identifier.urihttps://dx.doi.org/10.1007/s12032-010-9416-4
dc.identifier.urihttps://hdl.handle.net/20.500.12415/8334
dc.identifier.volume28en_US
dc.identifier.wosWOS:000287756000019en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherHUMANA PRESS INCen_US
dc.relation.ispartofMEDICAL ONCOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKY02885
dc.subjectHuman papillomavirusen_US
dc.subjectColorectal carcinomaen_US
dc.subjectAdenomaen_US
dc.subjectPolymerase chain reactionen_US
dc.subjectCarcinogenesisen_US
dc.titleInvestigation of human papillomavirus DNA in colorectal carcinomas and adenomasen_US
dc.typeArticle
dspace.entity.typePublication

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu