Palpable lesions as a diagnostic tool in patients with thoracic pathology

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dc.authorid0000-0002-6197-7654en_US
dc.authorid0000-0002-5539-2502en_US
dc.authorid0000-0001-7432-9827en_US
dc.contributor.authorYener, Nese Arzu
dc.contributor.authorMidi, Ahmet
dc.contributor.authorCubuk, Rahmi
dc.contributor.authorOrki, Alpay
dc.contributor.authorOnar, Cagatay
dc.contributor.authorErsev, Ayse
dc.contributor.authorArman, Bulent
dc.date.accessioned2024-07-12T21:46:09Z
dc.date.available2024-07-12T21:46:09Z
dc.date.issued2013en_US
dc.departmentMaltepe Üniversitesien_US
dc.description.abstractPalpable lesion(s) noticed in a patient with thoracic disease may be a useful diagnostic tool and it often gives a clue for further management. In this study, we searched the diagnostic value of palpable lesions in patients with thoracic pathology suspected clinically and/or radiologically. We prospectively examined the correlations of clinical/radiologic and pathologic findings of 72 palpable lesions from 68 patients who presented with suspect for a thoracic disease from two tertiary medical centers. Thirty-two lesions (44.4%) were diagnosed as malignant either by fine-needle aspiration (FNA) only or FNA with confirmatory biopsy. The most common malignancy was non-small-cell carcinoma (10) followed by adenocarcinoma (6), and small-cell carcinoma (5). The most common localization of the palpable lesions was cervical region (20.8%) followed by left supraclavicular (13.8%) and anterior chest wall (13.8%). FNA was effective in obtaining an accurate diagnosis in 66.6% of the patients. Tissue confirmation of FNA was performed in 54 patients. The sensitivity, specificity, negative predictive value, and positive predictive value of FNA in distinguishing a malignant lesion from a benign disease for these palpable lesions were 75, 97, 96, and 80, respectively. One false negativity and one false positivity were also found. Abnormal radiologic features were not correlated with having a malignant palpable lesion. Evaluation of the palpable lesions by FNA and tissue biopsy together is effective for initial triage of the patients with suspect for a thoracic pathology. FNA alone is a convenient and easy method for this purpose especially when the material is immediately assessed for specimen adequacy. Diagn. Cytopathol. 2013. (c) 2011 Wiley Periodicals, Inc.en_US
dc.identifier.doi10.1002/dc.21755
dc.identifier.endpage34en_US
dc.identifier.issn8755-1039
dc.identifier.issue1en_US
dc.identifier.pmid21681977en_US
dc.identifier.scopus2-s2.0-84872854884en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage28en_US
dc.identifier.urihttps://dx.doi.org/10.1002/dc.21755
dc.identifier.urihttps://hdl.handle.net/20.500.12415/7900
dc.identifier.volume41en_US
dc.identifier.wosWOS:000312546400005en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherWILEY-BLACKWELLen_US
dc.relation.ispartofDIAGNOSTIC CYTOPATHOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKY00634
dc.subjectcutaneous metastasisen_US
dc.subjectfine-needle aspirationen_US
dc.subjectpalpable lesionsen_US
dc.subjectthoracic pathologyen_US
dc.subjecttuberculous lymphadenitisen_US
dc.titlePalpable lesions as a diagnostic tool in patients with thoracic pathologyen_US
dc.typeArticle
dspace.entity.typePublication

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