Double-Edged Sword: A Case with Withdrawal-Emergent Dyskinesia

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dc.authoridKök Kendirlioğlu, Burcu/0000-0003-0632-1617en_US
dc.contributor.authorArat Çelik, Hidayet Ece
dc.contributor.authorKok-Kendirlioğlu, Burcu
dc.contributor.authorÇetin, Busra
dc.contributor.authorKucukgoncu, Suat
dc.date.accessioned2024-07-12T21:37:42Z
dc.date.available2024-07-12T21:37:42Z
dc.date.issued2021en_US
dc.department[Belirlenecek]en_US
dc.description.abstractTardive dyskinesia is defined as involuntary athetoid or choreiform movements that develop due to the use of neuroleptic drugs for at least a few months. Tongue, lower face, jaw, upper and lower extremities are the most affected parts of the body in tardive dyskinesia. Quality of life is negatively affected because of the low remission rates. Besides tardive dyskinesia, involuntary movements may appear after discontinuation, change or a reduction in the dose of antipsychotic medications, which is called withdrawal-emergent dyskinesia (WED). Unlike tardive dyskinesia, the involuntary movements involve mainly the neck, trunk, and limbs and regress in shorter period of time in WED. A consensus has not yet been reached for the treatment of WED. Restarting the previous antipsychotic agent with slow titration or switching to an atypical antipsychotic with low affinity for dopamine D2 receptors are among the primary options for treatment. As WED is one of the predictors of tardive dyskinesia development, early detection and treatment is believed to have positive effect on the quality of life. In this report, the case of a patient followed up for bipolar disorder type I (BD-I) and started on clozapine for WED after discontinuation of haloperidol on account of adverse effects is discussed. It is necessary for clinicians to consider these types of complications when discontinuing or changing treatment. Further research is needed in order to reach a common approach for the treatment of WED.en_US
dc.identifier.doi10.5080/u25613
dc.identifier.endpage285en_US
dc.identifier.issn1300-2163
dc.identifier.issue4en_US
dc.identifier.pmid34964103en_US
dc.identifier.scopus2-s2.0-85123056917en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage283en_US
dc.identifier.trdizinid516379en_US
dc.identifier.urihttps://doi.org/10.5080/u25613
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/516379
dc.identifier.urihttps://hdl.handle.net/20.500.12415/6890
dc.identifier.volume32en_US
dc.identifier.wosWOS:000770357100009en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isotren_US
dc.publisherTurkiye Sinir Ve Ruh Sagligi Dernegien_US
dc.relation.ispartofTurk Psikiyatri Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKY04232
dc.subjectWithdrawal-Emergent Dyskinesiaen_US
dc.subjectHaloperidolen_US
dc.subjectTardive Dyskinesiaen_US
dc.subjectAdverse Effecten_US
dc.titleDouble-Edged Sword: A Case with Withdrawal-Emergent Dyskinesiaen_US
dc.typeArticle
dspace.entity.typePublication

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