The value of surgical resection in patients with multidrug resistant tuberculosis

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dc.authorid0000-0001-7432-9827en_US
dc.authorid0000-0001-9169-560Xen_US
dc.contributor.authorOrki, Alpay
dc.contributor.authorKoşar, Altuğ
dc.contributor.authorDemirhan, Recep
dc.contributor.authorSaygı, A.
dc.contributor.authorArman, Bülent
dc.date.accessioned2024-07-12T21:11:46Z
dc.date.available2024-07-12T21:11:46Z
dc.date.issued2009en_US
dc.departmentFakülteler, Tıp Fakültesien_US
dc.description.abstractBackground: Multidrug resistant tuberculosis (MDR-TB) still continues to be a serious health problem throughout the world. Although main treatment of MDR-TB is medical, surgical resection with adjuvant medical therapy may increase the chance of cure in selected patients. Methods: We performed surgical resections in 55 patients between 1997 and 2005; 36 were male and 19 were female with a median age of 34 years (range 13 to 66 years). Sputum was negative for 49 patients and positive for 6 patients in the preoperative period. Patients were treated according to a new therapy protocol for a mean of 3.7 months before the operation. Results: Lobectomy was performed in 37 patients, pneumonectomy in 17 patients and lobectomy + segmentectomy in 1 patient. One patient with positive sputum preoperatively died in the early postoperative period (mortality: 1.81 %). Various complications occurred in 16 (29.09 %) patients. Prolonged air leak was the most common complication (n = 8). Bronchopleural fistula (BPF) + empyema occurred in 2 (3.63 %) patients. In the postoperative period, sputum negativity was achieved in all patients except three cases throughout the 57 months of follow-up (cure rate 94.5 %). Patients received drug therapy for 24 months postoperatively. Conclusions: Surgical resection with adjuvant drug therapy increases the chance of cure in patients with localized disease if they have an adequate cardiopulmonary reserve, favorable nutritional status and are treated with a new therapy protocol for at least 3 months.en_US
dc.identifier.citationOrki, A., Koşar, A., Demirhan, R., Saygı, A. ve Arman, B. (2009). The value of surgical resection in patients with multidrug resistant tuberculosis. The Thoracic and Cardiovascular Surgeon. 57(4), s. 222-225.en_US
dc.identifier.endpage225en_US
dc.identifier.issue4en_US
dc.identifier.startpage222en_US
dc.identifier.urihttps://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0029-1185458
dc.identifier.urihttps://hdl.handle.net/20.500.12415/4396
dc.identifier.volume57en_US
dc.institutionauthorKoşar, Altuğ
dc.language.isoenen_US
dc.publisherGeorg Thieme Verlag KGen_US
dc.relation.ispartofThe Thoracic and Cardiovascular Surgeonen_US
dc.relation.isversionof10.1055/s-0029-1185458en_US
dc.relation.publicationcategoryUluslararası Hakemli Dergide Makale - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKY03574
dc.titleThe value of surgical resection in patients with multidrug resistant tuberculosisen_US
dc.typeArticle
dspace.entity.typePublication

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