The relationship between serum adiponectin and resistin levels, insulin resistance and colorectal adenomas

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dc.authorid0000-0002-0326-5528en_US
dc.contributor.authorDemir, Nazli
dc.contributor.authorAhishali, Emel
dc.contributor.authorDolapcioglu, Can
dc.contributor.authorErcan, Serif
dc.contributor.authorKaptanagasi, Asuman Orcun
dc.contributor.authorDabak, Resat
dc.contributor.authorYucel, Nihal
dc.contributor.authorSargin, Mehmet
dc.contributor.authorBayramicli, Oya Uygur
dc.date.accessioned2024-07-12T21:56:38Z
dc.date.available2024-07-12T21:56:38Z
dc.date.issued2015en_US
dc.departmentMaltepe Üniversitesien_US
dc.description.abstractBackground/Aims: The relationship between adipocytokines and the development of colorectal cancer is well-documented. Our aim was to assess the relationship among serum adiponectin and resistin levels, insulin resistance, and colorectal adenoma to evaluate whether these parameters can be used as biomarkers to predict the development of colorectal adenoma. Materials and Methods: This is a cross-sectional case-control study conducted in 32 patients with colorectal adenoma and 30 control subjects. Serum adiponectin and resistin levels, body mass index values, waist and hip circumferences and Homeostasis Model Assessment scores were measured. Results: Resistin levels were slightly higher and adiponectin was slightly lower in patients with colorectal adenoma compared with controls; however, the differences in both parameters failed to reach statistical significance. The body mass index values and waist circumference of the patient group were significantly higher than controls (p=0.003 and p=0.002, respectively). Fasting serum insulin levels and Homeostasis Model Assessment scores of patients with colorectal adenoma were significantly higher than those of controls (p=0.02 and p=0.02, respectively). There was no relation between the number of colorectal adenomas and serum adiponectin or resistin levels. Conclusion: Our data indicate that obesity and insulin resistance may contribute to the development of colorectal adenoma and that serum adiponectin levels and insulin resistance may not have a substantial predictive value for colorectal adenoma.en_US
dc.identifier.doi10.5152/tjg.2015.3626
dc.identifier.endpage24en_US
dc.identifier.issn1300-4948
dc.identifier.issue1en_US
dc.identifier.pmid25698266en_US
dc.identifier.scopus2-s2.0-84922575053en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage20en_US
dc.identifier.trdizinid188378en_US
dc.identifier.urihttps://dx.doi.org/10.5152/tjg.2015.3626
dc.identifier.urihttps://hdl.handle.net/20.500.12415/8571
dc.identifier.volume26en_US
dc.identifier.wosWOS:000351642900005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherAVESen_US
dc.relation.ispartofTURKISH JOURNAL OF GASTROENTEROLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKY03697
dc.subjectColorectal adenomaen_US
dc.subjectadiponectinen_US
dc.subjectresistinen_US
dc.subjectinsulin resistanceen_US
dc.subjectobesityen_US
dc.titleThe relationship between serum adiponectin and resistin levels, insulin resistance and colorectal adenomasen_US
dc.typeArticle
dspace.entity.typePublication

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