Procalcitonin in the diagnosis of sepsis and correlations with upcoming novel diagnostic markers

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dc.authorid0000-0001-5114-8660en_US
dc.authorid0000-0002-2998-263Xen_US
dc.authorid0000-0003-3799-1090en_US
dc.contributor.authorSitar, Mustafa Erinç
dc.contributor.authorÖngen İpek, Belkız
dc.contributor.authorKaradeniz, Aslı
dc.date.accessioned2024-07-12T21:04:15Z
dc.date.available2024-07-12T21:04:15Z
dc.date.issued2019en_US
dc.departmentFakülteler, Tıp Fakültesien_US
dc.description.abstractSepsis is a complex and lethal condition. For successful treatment, clinicians need high quality testing to guide the approach to pathogen identification and treatment. Medical laboratories play a vital role in the detection of infectious agents, and must continually strive to discover new and reliable tests and to analyze the reliability of existing tests in different diseases and expand their usage as appropriate. Selecting the appropriate therapy, reducing the use of antibiotics and thereby reducing antibiotic resistance are also undeniable parts of this task. The most commonly used parameters to guide infection therapy are the white blood cell count, the erythrocyte sedimentation rate, the absolute count of neutrophils, the absolute number of lymphocytes, and the level of C-reactive protein, serum amyloid A protein, ceruloplasmin, haptoglobin, fibrinogen, and procalcitonin (ProCT). Although ProCT has been accepted as quite effective in differentiating serious bacterial infections, there are unresolved questions regarding effective usage during follow-up, as there are with other markers. ProCT and other promising biomarkers in a sepsis setting were the focus of this review, beginning with the first study to define ProCT in the literature, and examining some of the studies related to the importance of the ProCT-sepsis relationship, and detailed information on candidate markers.en_US
dc.identifier.citationSitar, M.E., Öngen İpek, B. ve Karadeniz, A. (2019). Procalcitonin in the diagnosis of sepsis and correlations with upcoming novel diagnostic markers. International Journal of Medical Biochemistry, Association of Clinical Biochemistry Specialists Turkey. 2(3), s. 132-140.en_US
dc.identifier.doi10.14744/ijmb.2019.30502
dc.identifier.endpage140en_US
dc.identifier.issn2618-642X
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85118151742en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage132en_US
dc.identifier.trdizinid331830en_US
dc.identifier.urihttps://internationalbiochemistry.com/jvi.aspx?un=IJMB-30502&volume=
dc.identifier.urihttps://doi.prg/10.14744/ijmb.2019.30502
dc.identifier.urihttps://hdl.handle.net/20.500.12415/3769
dc.identifier.volume2en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.institutionauthorSitar, Mustafa Erinç
dc.institutionauthorÖngen İpek, Belkız
dc.institutionauthorKaradeniz, Aslı
dc.language.isoenen_US
dc.publisherAssociation of Clinical Biochemistry Specialists Turkeyen_US
dc.relation.ispartofInternational Journal of Medical Biochemistryen_US
dc.relation.publicationcategoryUluslararası Hakemli Dergide Makale - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKY01663
dc.subjectBiomarkeren_US
dc.subjectC-reactive proteinen_US
dc.subjectprocalcitoninen_US
dc.subjectreference intervalen_US
dc.subjectsepsisen_US
dc.titleProcalcitonin in the diagnosis of sepsis and correlations with upcoming novel diagnostic markersen_US
dc.typeArticle
dspace.entity.typePublication

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