Alcohol-dependent patients attempting and not attempting suicide: a comparison

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dc.contributor.authorPektas, O
dc.contributor.authorMirsal, H
dc.contributor.authorKalyoncu, A
dc.contributor.authorUnsalan, N
dc.contributor.authorBeyazyurek, M
dc.date.accessioned2024-07-12T21:44:18Z
dc.date.available2024-07-12T21:44:18Z
dc.date.issued2004en_US
dc.departmentMaltepe Üniversitesien_US
dc.description.abstractBackground: Alcohol dependence is a psychiatric disorder associated with an increased risk of suicidal behaviour. This is also associated with an increased number of suicide risk factors. Objective: The current study examined the sociodemographic and clinical characteristics of a number of alcohol-dependent patients who attempted suicide. Methods: We studied a consecutive series of 377 alcohol-dependent patients in our in-patient clinics. Their alcohol-use histories were assessed through semistructured interviews. The Suicidal Behaviors Questionnaire, the Childhood Trauma Questionnaire, the Michigan Alcoholism Screening Test and the Hamilton Depression Rating Scale were administered to all patients. Serum total cholesterol levels, mean corpuscular volume, the liver enzymes gamma glutamyl transferase, aspartate aminotransferase and alanine aminotransferase were routinely measured. In the statistical analyses, Student's t-test and chi-squared tests were applied. Results: Of the 377 alcohol-dependent patients, 89 (23.6%) had histories of attempted suicide. Thirty-four (42.5%) of the 80 female alcohol-dependent patients and 55 (18.5%) of the 297 male alcohol-dependent patients had attempted suicide; this gender difference was statistically significant (chi(2) = 27.7, P < 0.001). A greater proportion of the suicide attempters than of the non-attempters met the Diagnostic Statistical Manual IV criteria for another psychiatric disorder (60.6%, n = 54, vs. 40.6%, n = 117; chi(2) = 14.8; df = 6; P < 0.05). The difference of total cholesterol levels between female (mean = 144.0, SD = 58.3; mean = 158.0, SD = 83.9; t = 4.5; P < 0.05) and male (mean = 133.7, SD = 50.5; mean = 163.6, SD = 69.7; t = 11.7; P < 0.01) attempters and non-attempters was statistically significant. Conclusion: These results suggest that suicide attempts in alcohol-dependent patients are associated with more profound biopsychosocial pathology and decreased serum cholesterol levels.en_US
dc.identifier.doi10.1111/j.0924-2708.2004.00088.x
dc.identifier.endpage211en_US
dc.identifier.issn1601-5215
dc.identifier.issue4en_US
dc.identifier.pmid26984308en_US
dc.identifier.scopus2-s2.0-10844271679en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage204en_US
dc.identifier.urihttps://dx.doi.org/10.1111/j.0924-2708.2004.00088.x
dc.identifier.urihttps://hdl.handle.net/20.500.12415/7710
dc.identifier.volume16en_US
dc.identifier.wosWOS:000226246100004en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherCAMBRIDGE UNIV PRESSen_US
dc.relation.ispartofACTA NEUROPSYCHIATRICAen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKY00050
dc.subjectalcohol dependenceen_US
dc.subjectbiochemical markersen_US
dc.subjectcharacteristicsen_US
dc.subjectcholesterolen_US
dc.subjectsuicideen_US
dc.titleAlcohol-dependent patients attempting and not attempting suicide: a comparisonen_US
dc.typeArticle
dspace.entity.typePublication

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