The diagnosis of non-hodgkin’s lymphoma in epidermodysplasia verruciformis patient

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dc.authorid0000-0002-2226-124Xen_US
dc.authorid0000-0001-8207-4940en_US
dc.authorid0000-0003-1493-4579en_US
dc.authorid0000-0002-4075-6692en_US
dc.contributor.authorKaragöz, Bülent
dc.contributor.authorAkyol Erikçi, Alev
dc.contributor.authorKarabudak, Özlem
dc.contributor.authorBilgi, Oğuz
dc.contributor.authorSayan, Özkan
dc.contributor.authorKandemir, E. Gökhan
dc.contributor.authorÖztürk, Ahmet
dc.date.accessioned2024-07-12T21:14:05Z
dc.date.available2024-07-12T21:14:05Z
dc.date.issued2005en_US
dc.departmentFakülteler, Tıp Fakültesien_US
dc.description.abstractEpidermodysplasia verruciformis (EV) is a rare, multifactorial disorder. This disease contains genetic and immunologic components and accompanies infection with some specific Human Papilloma Virus (HPV) types. The patients may develop multiple in situ and/or invasive squamous cell carcinomas. The most of the patients have impaired cell-mediated immunity. Although EV accompanies frequently skin cancer and extracutanous squamous cell carcinoma, the association between EV and other cancers is not described. In this report, a case of EV with primary mediastinal large B cell lymphoma is presented. A 20-year-old man was seen in our outpatient clinic. He had red-brown macular lesions in sun exposed areas as face and neck for five years duration. EV was diagnosed by histopathologic examination of skin biopsy. One month later, he started to cough. The histological diagnosis of mediastinal mass measuring 6 cm in diameter was diffuse large Bcell lymphoma. B symptoms were absent. He was diagnosed to have stage IAX disease. R-CHOP chemotherapy (Rituximab plus CHOP) and involved field radiotherapy were administered. We have been following this case for 6 months and complete remission is achieved. EV accompanies infection with specific HPV types and is seen in immunosuppressive patients. Some of EV-specific HPVs, particularly HPV 5 and 8 have oncogenic properties. These may have also lymphogenic effect. Moreover the lymphomas are seen frequently in immunosuppressive patients. We conclude that EV may be a predisposition for lymphoma.en_US
dc.identifier.citationKaragöz, B., Akyol Erikçi, A., Karabudak, Ö., Bilgi, O., Sayan, Ö., Türken, O., Kandemir, E. G. ve Öztürk, A. (2005). The diagnosis of non-hodgkin’s lymphoma in epidermodysplasia verruciformis patient. XXX th World Congress of the International Society of Hematology, Turkish Society of Hematology. 22(3), s. 263.en_US
dc.identifier.endpage263en_US
dc.identifier.issn1308-5263
dc.identifier.issue3en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage263en_US
dc.identifier.urihttps://jag.journalagent.com/tjh/pdfs/TJH_22_SUP_3_251_300.pdf
dc.identifier.urihttps://hdl.handle.net/20.500.12415/4588
dc.identifier.volume22en_US
dc.institutionauthorTürken, Orhan
dc.language.isoenen_US
dc.publisherTurkish Society of Hematologyen_US
dc.relation.ispartofXXX th World Congress of the International Society of Hematologyen_US
dc.relation.publicationcategoryUluslararası Konferans Öğesien_US
dc.rightsCC0 1.0 Universal*
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rights.urihttp://creativecommons.org/publicdomain/zero/1.0/*
dc.snmzKY08683
dc.titleThe diagnosis of non-hodgkin’s lymphoma in epidermodysplasia verruciformis patienten_US
dc.typeConference Object
dspace.entity.typePublication

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