Lung cancer and pregnancy

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dc.authorid0000-0003-3311-3338en_US
dc.contributor.authorSariman, Nesrin
dc.contributor.authorLevent, Ender
dc.contributor.authorYener, Nese Arzu
dc.contributor.authorOrki, Alpay
dc.contributor.authorSaygi, Attila
dc.date.accessioned2024-07-12T21:51:45Z
dc.date.available2024-07-12T21:51:45Z
dc.date.issued2013en_US
dc.departmentMaltepe Üniversitesien_US
dc.description.abstractLung cancer in the pregnant woman is a very rare and dramatic coincidence with poor prognosis. Treatment depends on the gestational week of the pregnancy, patient's medical status, social, personal, familial, and even religious beliefs. We present a case of adenocarcinoma of the lung in a 34-year-old pregnant patient whose initial complaints were cough, dyspnea, fever and fatigue. She was diagnosed with pneumonia at another hospital, and antibiotic therapy was administered. Meanwhile, at 28 weeks she delivered a preterm low-birth-weight baby. Chest X-ray and thorax CT revealed a mass lesion in the upper left lung lobe. After admission to our clinic, needle aspiration of left supraclavicular lymph node and bronchoscopic biopsy from upper lobe bronchus showed a non-small lung cancer; adenocarcinoma. Brain MRI was normal. PET CT revealed multiple bone metastases. Multidisciplinary Tumor Committee at our hospital referred her to the Oncology Department as an advanced stage IV disease. Chemotherapy was administered with paclitaxel and carboplatin for a total of 12 weeks. Reassessment of the patient revealed new bone metastases and crizotinib was administered since her tumor was found positive for EML4-ALK mutations. The treatment was well tolerated. During a follow up period of 6 months her clinical condition was stable and no adverse events were encountered. (c) 2012 Elsevier Ireland Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.lungcan.2012.11.014
dc.identifier.endpage323en_US
dc.identifier.issn0169-5002
dc.identifier.issue3en_US
dc.identifier.pmid23254266en_US
dc.identifier.scopus2-s2.0-84873189401en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage321en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.lungcan.2012.11.014
dc.identifier.urihttps://hdl.handle.net/20.500.12415/8312
dc.identifier.volume79en_US
dc.identifier.wosWOS:000315238900021en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherELSEVIER IRELAND LTDen_US
dc.relation.ispartofLUNG CANCERen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKY02199
dc.subjectLung cancer in pregnancyen_US
dc.subjectAdenocarcinomaen_US
dc.subjectDiagnosisen_US
dc.subjectSmokingen_US
dc.titleLung cancer and pregnancyen_US
dc.typeArticle
dspace.entity.typePublication

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