Comparison of diagnostic accuracy of saline infusion sonohysterography, transvaginal sonography and hysteroscopy in postmenopausal bleeding

dc.contributor.authorBingol, Banu
dc.contributor.authorGunenc, M. Ziya
dc.contributor.authorGedikbasi, Ali
dc.contributor.authorGuner, Haldun
dc.contributor.authorTasdemir, Seval
dc.contributor.authorTiras, Bulent
dc.date.accessioned2024-07-12T21:45:06Z
dc.date.available2024-07-12T21:45:06Z
dc.date.issued2011en_US
dc.departmentMaltepe Üniversitesien_US
dc.description.abstractTo compare the diagnostic accuracy of transvaginal sonography (TVS), saline infusion sonohysterography (SIS) and hysteroscopy (HS) with respect to pathological diagnosis in the detection of uterine cavity abnormalities associated with abnormal uterine bleeding among postmenopausal women. Being a prospective, investigator-blind trial, the present study was conducted on 137 postmenopausal women, with abnormal uterine bleeding, admitted to the Department of Obstetrics and Gynecology of Istanbul Bilim University, Florence Nightingale Hospital and Fertigyn Woman Health and IVF Center. After TVS, all patients underwent SIS using Cook Soft 500 IVF transfer catheter and HS, consecutively. Sensitivity, specificity, and positive and negative predictive values (PPV and NPV) were calculated to compare the diagnostic accuracy of TVS, SIS and HS. Most commonly encountered endometrial lesions were polypoid lesion (38.0%) and hyperplasia (28.4%) among our study population consisting of 137 women (mean age 61.6 +/- A 9.6 years) in their postmenopausal stage. Overall sensitivity rates were 70.0% for TVS, 89.6% for SIS and 92.3% for HS, while the overall specificity rates were 50.0, 77.3 and 80.7%, respectively. HS had PPV of 96.2% and NPV of 65.3%, whereas PPV was determined to be 80.9 versus 95.3% and NPV was 35.4 versus 58.3% for TVS and SIS, respectively. As an easy to perform, safe and well-tolerated procedure yielding high diagnostic accuracy, saline infusion SIS via this catheter seems to be superior to TVS and very close to HS. It may be used as the primary method for the detection of uterine abnormalities among postmenopausal women with abnormal uterine bleeding.en_US
dc.identifier.doi10.1007/s00404-010-1604-0
dc.identifier.endpage117en_US
dc.identifier.issn0932-0067
dc.identifier.issue1en_US
dc.identifier.pmid20665218en_US
dc.identifier.scopus2-s2.0-79958814826en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage111en_US
dc.identifier.urihttps://dx.doi.org/10.1007/s00404-010-1604-0
dc.identifier.urihttps://hdl.handle.net/20.500.12415/7794
dc.identifier.volume284en_US
dc.identifier.wosWOS:000291482900018en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSPRINGER HEIDELBERGen_US
dc.relation.ispartofARCHIVES OF GYNECOLOGY AND OBSTETRICSen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKY00320
dc.subjectTransvaginal sonographyen_US
dc.subjectSaline infusion sonohysterographyen_US
dc.subjectHysteroscopyen_US
dc.subjectPostmenopausal bleedingen_US
dc.subjectUterine cavityen_US
dc.subjectDiagnostic accuracyen_US
dc.titleComparison of diagnostic accuracy of saline infusion sonohysterography, transvaginal sonography and hysteroscopy in postmenopausal bleedingen_US
dc.typeArticle
dspace.entity.typePublication

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