Feasibility of imprint cytology for evaluation of mediastinal lymph nodes in lung cancer

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dc.authorid0000-0001-7432-9827en_US
dc.authorid0000-0001-9169-560Xen_US
dc.contributor.authorOrki, Alpay
dc.contributor.authorTezel, Çağatay
dc.contributor.authorKoşar, Altuğ
dc.contributor.authorErsev, Ayşe Alp
dc.contributor.authorDudu, Canan
dc.contributor.authorArman, Bülent
dc.date.accessioned2024-07-12T21:04:30Z
dc.date.available2024-07-12T21:04:30Z
dc.date.issued2006en_US
dc.departmentFakülteler, Tıp Fakültesien_US
dc.description.abstractBackground: Intraoperative evaluation of mediastinal lymph nodes is a necessary step which helps us to decide whether or not to continue the operation of lung cancer. Imprint cytology (IC) can be used as an alternative method in staging. It is a more rapid and simpler procedure than frozen section (FS) analysis. Therefore, we compared the diagnostic accuracy of IC with permanent section on 1050 mediastinal lymph nodes. Methods: A total of 255 non-small cell lung cancer patients who underwent surgical procedure between January 1995 and April 2004 were included. There were 236 males and 19 females with a mean age of 54.2 years (range 26-79 years). In order to obtain lymph node samples mediastinoscopy was performed in 232 (91%), anterior mediastinotomy in 50 (20%) and video-assisted thoracoscopic surgery in 16 (6.3%) patients. During final pathological diagnosis, both imprint and permanent section slides were compared. Results: There were five false-positive and eight false-negative results. The sensitivity, specificity and the predictive values for positive and negative results were 93.1, 99.5, 95.6 and 99.1%, respectively. The overall efficiency was 98.8%. Conclusions: The diagnostic IC is an accurate, reliable, simple and less time-consuming method for evaluation of mediastinal lymph nodes in lung cancer, compared with FS method.en_US
dc.identifier.citationOrki, A., Tezel, Ç., Koşar, A., Ersev, A. A., Dudu, C. ve Arman, B. (2006). Feasibility of imprint cytology for evaluation of mediastinal lymph nodes in lung cancer. Japanese Journal of Clinical Oncology. 36(2), s. 76-79.en_US
dc.identifier.endpage79en_US
dc.identifier.issue2en_US
dc.identifier.startpage76en_US
dc.identifier.urihttps://pubmed.ncbi.nlm.nih.gov/16436461/
dc.identifier.urihttps://hdl.handle.net/20.500.12415/3789
dc.identifier.volume36en_US
dc.institutionauthorKoşar, Altuğ
dc.language.isoenen_US
dc.publisherNational Center for Biotechnology Informationen_US
dc.relation.ispartofJapanese Journal of Clinical Oncologyen_US
dc.relation.isversionof10.1093/jjco/hyi226en_US
dc.relation.publicationcategoryUlusal Hakemli Dergide Makale - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKY01772
dc.titleFeasibility of imprint cytology for evaluation of mediastinal lymph nodes in lung canceren_US
dc.typeArticle
dspace.entity.typePublication

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