Prediction of viability by pulsed-wave Doppler tissue sampling of asynergic myocardium during low-dose dobutamine challenge

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dc.authorid0000-0001-6945-0745en_US
dc.contributor.authorAltinmakas, S
dc.contributor.authorDagdeviren, B
dc.contributor.authorUyan, C
dc.contributor.authorKeser, N
dc.contributor.authorGumus, V
dc.contributor.authorPektas, O
dc.date.accessioned2024-07-12T21:49:47Z
dc.date.available2024-07-12T21:49:47Z
dc.date.issued2000en_US
dc.departmentMaltepe Üniversitesien_US
dc.description.abstractDobutamine stress echocardiography is widely used to predict reversible left ventricular dysfunction, but evaluation with this method is subjective. Pulsed-wave tissue Doppler imaging is a new technique that allows to obtain quantitative data on wall motion velocities of different myocardial segments through sample-volume placement. Therefore, this tool in combination with DSE may be suitable for identifying viability in asynergic myocardium. To evaluate this, in 40 patients (mean age 57+/-9) with resting dyssynergy (akinesis in 52, hypokinesis in 30) baseline wall motion scores and tissue Doppler variables were collected before and after 5 min infusion of 10 mu g/kg per min dobutamine. Forty-six of 82 segments were classified as viable (a reduction in segmental score of at least one grade) according to follow-up echocardiography that was performed 4 weeks after revascularization. While myocardial S velocity percent increase in viable segments was 45+/-10, the increase was 25+/-12 in necrotic segments (n=36) during 10 mu g dobutamine infusion (P=0.0001). Assuming 35% as a cut-off for viability the increase in S velocities by DSE yielded an 89% sensitivity and 86% specificity for predicting post-revascularization functional recovery. In conclusion, pulsed-wave tissue Doppler imaging of asynergic myocardium during dobutamine stress echocardiography can identify the viability quantitatively. (C) 2000 Elsevier Science Ireland Ltd. All nights reserved.en_US
dc.identifier.doi10.1016/S0167-5273(00)00226-6
dc.identifier.endpage113en_US
dc.identifier.issn0167-5273
dc.identifier.issue2.Maren_US
dc.identifier.pmid10962109en_US
dc.identifier.scopus2-s2.0-0343442382en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage107en_US
dc.identifier.urihttps://dx.doi.org/10.1016/S0167-5273(00)00226-6
dc.identifier.urihttps://hdl.handle.net/20.500.12415/8080
dc.identifier.volume74en_US
dc.identifier.wosWOS:000089568800001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherELSEVIER SCI IRELAND LTDen_US
dc.relation.ispartofINTERNATIONAL JOURNAL OF CARDIOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKY01276
dc.subjecttissue Doppleren_US
dc.subjectviabilityen_US
dc.subjectdobutamine stress testen_US
dc.titlePrediction of viability by pulsed-wave Doppler tissue sampling of asynergic myocardium during low-dose dobutamine challengeen_US
dc.typeArticle
dspace.entity.typePublication

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