Supernumerary ectopic parathyroid glands. Persistent hyperparathyroidism due to mediastinal parathyroid adenoma localized by preoperative single photon emission computed tomography and intraoperative gamma probe application

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dc.contributor.authorUludag, Mehmet
dc.contributor.authorIsgor, Adnan
dc.contributor.authorYetkin, Guerkan
dc.contributor.authorAtay, Murat
dc.contributor.authorKebudi, Abut
dc.contributor.authorAkgun, Ismail
dc.date.accessioned2024-07-12T21:47:20Z
dc.date.available2024-07-12T21:47:20Z
dc.date.issued2009en_US
dc.departmentMaltepe Üniversitesien_US
dc.description.abstractEctopic and/or supernumerary parathyroid glands are a major cause of persistent and recurrent Hyperparathyroidism (HPT). For this reason, it is widely accepted that preoperative localization should be performed to improve the surgical results in patients with persistent or recurrent HPT. Primary HPT (pHPT) was diagnosed incidentally in a 50-year old female patient during a preoperative examination for hernia. No pathologic parathyroid gland was detected in the preoperative Tc-99m Methoxybutylisonitrile (MIBI) scintigraphy and Ultrasonography (US). Cervical exploration was performed bilaterally. Four parathyroid glands were located adjacent to the thyroid gland. A fifth was detected in front of the cricoid cartilage. All five of them were of normal histology. Postoperatively, hypercalcemia persisted. Single Photon Emission Computed Tomography (SPECT) was performed before the second operation and radioguide surgery was carried out by median sternotomy. SPECT showed a parathyroid adenoma in the middle of the anterior mediastinum which was excised (size 1x0.5x0.5 cm) using a gamma probe. In conclusion, SPECT and intraoperative gamma probe application may help to detect the parathyroid adenomas, especially if they are small in size and buried in the adipose tissue. Such localization shortens the duration of the operation and reduces the possibility of complications.en_US
dc.identifier.doi10.14310/horm.2002.1231
dc.identifier.endpage149en_US
dc.identifier.issn1109-3099
dc.identifier.issue2en_US
dc.identifier.pmid19570742en_US
dc.identifier.scopus2-s2.0-69149084411en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage144en_US
dc.identifier.urihttps://dx.doi.org/10.14310/horm.2002.1231
dc.identifier.urihttps://hdl.handle.net/20.500.12415/8033
dc.identifier.volume8en_US
dc.identifier.wosWOS:000267425600007en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherHELLENIC ENDOCRINE SOCen_US
dc.relation.ispartofHORMONES-INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISMen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKY01192
dc.subjectIntraoperative gamma probeen_US
dc.subjectMediastinal parathyroiden_US
dc.subjectPersistent hyperparathyroidismen_US
dc.subjectSPECTen_US
dc.subjectSupernumerary parathyroiden_US
dc.titleSupernumerary ectopic parathyroid glands. Persistent hyperparathyroidism due to mediastinal parathyroid adenoma localized by preoperative single photon emission computed tomography and intraoperative gamma probe applicationen_US
dc.typeArticle
dspace.entity.typePublication

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