Does leptin play a role in idiopathic thrombocytopenic purpura

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dc.authorid0000-0002-4075-6692en_US
dc.authorid0000-0002-3636-3853en_US
dc.contributor.authorAkyol Erikçi, Alev
dc.contributor.authorSayan, Özkan
dc.contributor.authorÇağlayan, Sinan
dc.contributor.authorÖztürk, Ahmet
dc.contributor.authorNarin, Yavuz
dc.date.accessioned2024-07-12T21:14:05Z
dc.date.available2024-07-12T21:14:05Z
dc.date.issued2005en_US
dc.departmentFakülteler, Tıp Fakültesien_US
dc.description.abstractBackground:Idiopathic thrombocytopenic purpura (ITP) is an immune disorder characterized by accelerated platelet destruction. Aim: We wanted to evaluate serum leptin levels in ITP, in order to determine the role of leptin on the pathogenesis of ITP.Methods: Twenty-three untreated patients with chronic ITP were compared with 15 healthy people of similar age, sex and body mass index (BMI). Serum leptin levels were measured by immunoradiometric assay (IRMA). Results:We found that the mean serum leptin levels in patients with ITP (26.71 +/- 17.69 ng/mL) were significantly (P < 0.001) higher than that in healthy control volunteers (6.54 +/- 4.36 ng/mL). Serum leptin levels in patients with ITP were inversely related (P < 0.001) to the platelet counts. Conclusion: We conclude that these findings suggest that leptin might be an independent factor in the pathogenesis of ITP.en_US
dc.identifier.citationAkyol Erikçi, A., Sayan, Ö., Türken, O., Çağlayan, S., Öztürk, A. ve narin, Y. (2005). Does leptin play a role in idiopathic thrombocytopenic purpura. XXX th World Congress of the International Society of Hematology, Turkish Society of Hematology. 22(3), s. 266-267.en_US
dc.identifier.endpage267en_US
dc.identifier.issn1308-5263
dc.identifier.issue3en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage266en_US
dc.identifier.urihttps://jag.journalagent.com/tjh/pdfs/TJH_22_SUP_3_251_300.pdf
dc.identifier.urihttps://hdl.handle.net/20.500.12415/4587
dc.identifier.volume22en_US
dc.institutionauthorTürken, Orhan
dc.language.isoenen_US
dc.publisherTurkish Society of Hematologyen_US
dc.relation.ispartofXXX th World Congress of the International Society of Hematologyen_US
dc.relation.publicationcategoryUluslararası Konferans Öğesien_US
dc.rightsCC0 1.0 Universal*
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rights.urihttp://creativecommons.org/publicdomain/zero/1.0/*
dc.snmzKY08682
dc.titleDoes leptin play a role in idiopathic thrombocytopenic purpuraen_US
dc.typeConference Object
dspace.entity.typePublication

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