Electron microscopic immunolocalization of basic fibroblast growth factor in peripheral nerves

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dc.authorid0000-0002-4474-7371en_US
dc.contributor.authorKayton, Robert J.
dc.date.accessioned2024-07-12T21:04:03Z
dc.date.available2024-07-12T21:04:03Z
dc.date.issued2000en_US
dc.departmentFakülteler, Tıp Fakültesien_US
dc.description.abstractIn spite of ample information about the distribution and the effects of basic fibroblast growth factor (bFGF) in the central nervous system, few data are available concerning the localization of this protein in the peripheral nervous system. In view of the role of bFGF in the regulation of trophic and non-trophic functions, we focused on the presence and precise localization of this growth factor in normal peripheral nerves at the electron microscopic level. The study shows that bFGF is mainly located in the Schwann cells, especially in the nuclei. There is slight labeling in the myelin sheath and in the axon cytoplasm. The study provides morphologic evidence for an association between bFGF expression and Schwann cells. Such as association argues for a role of this peptide in the maintenance or regeneration of peripheral nerves.en_US
dc.identifier.citationKayton R.J. ve Aktas, R.G. (2000). Electron microscopic immunolocalization of basic fibroblast growth factor in peripheral nerves. Histochemistry and Cell Biology, Springerlink. 114(5), s. 413-419.en_US
dc.identifier.endpage419en_US
dc.identifier.issn0948-6143
dc.identifier.issn1432-119X
dc.identifier.issue5en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage413en_US
dc.identifier.urihttps://link.springer.com/article/10.1007%2Fs004180000200
dc.identifier.urihttps://hdl.handle.net/20.500.12415/3747
dc.identifier.volume114en_US
dc.institutionauthorAktas, Ranan Gulhan
dc.language.isoenen_US
dc.publisherSpringerlinken_US
dc.relation.ispartofHistochemistry and Cell Biologyen_US
dc.relation.isversionof10.1007/s004180000200en_US
dc.relation.publicationcategoryUluslararası Hakemli Dergide Makale - Kurum Öğretim Elemanıen_US
dc.rightsCC0 1.0 Universal*
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rights.urihttp://creativecommons.org/publicdomain/zero/1.0/*
dc.snmzKY01188
dc.subjectBasic fibroblast growth factoren_US
dc.subjectImmunoelectron microscopyen_US
dc.titleElectron microscopic immunolocalization of basic fibroblast growth factor in peripheral nervesen_US
dc.typeArticle
dspace.entity.typePublication

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