Diagnostic accuracy of metastatic axillary lymph nodes in breast MRI

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dc.authorid0000-0002-6253-3318en_US
dc.contributor.authorArslan, Gozde
dc.contributor.authorAltintoprak, Kubra Murzoglu
dc.contributor.authorYirgin, Inci Kizildag
dc.contributor.authorAtasoy, Mehmet Mahir
dc.contributor.authorCelik, Levent
dc.date.accessioned2024-07-12T21:53:23Z
dc.date.available2024-07-12T21:53:23Z
dc.date.issued2016en_US
dc.departmentMaltepe Üniversitesien_US
dc.description.abstractPurpose: The most important prognostic variable for early stage breast cancer is the status of axillary lymph nodes. The aim of this study was to evaluate the diagnostic accuracy of preoperative magnetic resonance imaging (MRI) for metastatic axillary lymph node in breast cancer cases with post-operative sentinel lymph node biopsy (SLNB) results. Materials and methods: Women aged between 21 and 73 years who were diagnosed with malignant mass lesion of the breast between 2013 and 2015 were included in this study. The preoperative MR images of patients with diagnosis of breast cancer was evaluated to determine axillary lymph node status. Axillary lymph node size, long axis to short axis ratio, lymph node contours, cortical thickness to anteroposterior diameter ratio, the presence of a fatty hilum and contrast enhancement patterns (homogenous or heterogenous) was noted. Additionally, the presence of comet tail sign which a tail extending from an enhancing breast lesion into the parenchyma and might represent ductal infiltration on post-contrast series was also noted. All data obtained from this evaluation was compared with postoperative SLNB results. Results: Metastatic nodes were found to have a longer short axis when compared to reactive nodes (p = 0.042; p < 0.05). The long axis to short axis ratio was notably lower in metastatic nodes when compared to reactive nodes. Cortical thickness was higher in metastatic nodes when compared to reactive nodes (p = 0.024; p < 0.05). Comet sign was observed in 15 of metastatic nodes (73.3 %) and in one (5 %) reactive node. This difference was statistically significant (p = 0.001; p < 0.01). While fatty hilum was seen in 40 % of metastatic nodes (n = 6), it was seen in all (n = 20) reactive nodes. This difference was statistically significant (p = 0.001; p < 0.01). Conclusions: MRI is a non invasive sensitive and specific imaging modality for evaluating the axilla. We have shown that with the help of comet tail sign and status of fatty hilum contrast enhanced MRI has the highest sensitivity of 84.7 % for detecting axillary lymph node metastases (Singletary et al. in Semin Surg Oncol 21(1):53-59, 2003).en_US
dc.identifier.doi10.1186/s40064-016-2419-7
dc.identifier.issn2193-1801
dc.identifier.pmid27376003en_US
dc.identifier.scopus2-s2.0-84975882014en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.urihttps://dx.doi.org/10.1186/s40064-016-2419-7
dc.identifier.urihttps://hdl.handle.net/20.500.12415/8491
dc.identifier.volume5en_US
dc.identifier.wosWOS:000377972900012en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSPRINGER INTERNATIONAL PUBLISHING AGen_US
dc.relation.ispartofSPRINGERPLUSen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKY03443
dc.subjectAxillaen_US
dc.subjectMRIen_US
dc.subjectLymph nodeen_US
dc.titleDiagnostic accuracy of metastatic axillary lymph nodes in breast MRIen_US
dc.typeArticle
dspace.entity.typePublication

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