Diagnostic value of ischaemia-modified albumin for predicting myocardial ischaemia during myocardial perfusion scintigraphy
Küçük Resim Yok
Tarih
2008
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Sage Journals
Erişim Hakkı
CC0 1.0 Universal
info:eu-repo/semantics/openAccess
info:eu-repo/semantics/openAccess
Özet
During acute ischaemia the N-terminal site of albumin is altered, reducing its binding capacity; the modified protein is termed ischaemia-modified albumin (IMA). IMA is a sensitive marker of acute myocardial ischaemia but its diagnostic value in chronic angina pectoris patients is unclear. We investigated changes in blood levels of IMA during myocardial perfusion scintigraphy in patients with chronic angina pectoris in a study including 26 male and 20 female patients, with mean age 60 years. Technetium 99m perfusion imaging detected myocardial ischaemia in 26 patients. Coronary angiography was carried out in these 26 ischaemic patients. Mean IMA values at rest and peak exercise were significantly higher in the ischaemic than the non-ischaemic group. All IMA values were considered negative for cardiac ischaemia. Peak exercise IMA was significantly lower than the pre-exercise level only in the non-ischaemic group. IMA measurements during myocardial perfusion scintigraphy are not helpful in the diagnosis of myocardial ischaemia in patients with stable angina pectoris.
Açıklama
Anahtar Kelimeler
Myocardial ischaemia, Diagnosis, Angina Pectoris, Ischaemia-modified albumin, Myocardial perfusion scintigraphy
Kaynak
Journal of International Medical Research
WoS Q Değeri
Scopus Q Değeri
Q3
Cilt
36
Sayı
1
Künye
Cingozbay, B. Y., Ozmen, N., Canbolat, N., Aparci, M., Kardeşoğlu, E., Narin, Y., Gultepe, M., Cebeci, B. S. ve Dincturk, M. (2008). Diagnostic value of ischaemia-modified albumin for predicting myocardial ischaemia during myocardial perfusion scintigraphy. The Journal of international medical research, Sage Journals. 36(1), s. 147–151.
