Profile of gallbladder diseases diagnosed at Afyon Kocatepe University: A retrospective study

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dc.contributor.authorMazlum M.
dc.contributor.authorDilek F.H.
dc.contributor.authorYener A.N.
dc.contributor.authorTokyol Ç.
dc.contributor.authorAktepe F.
dc.contributor.authorDilek O.N.
dc.date.accessioned2024-07-12T21:53:54Z
dc.date.available2024-07-12T21:53:54Z
dc.date.issued2011en_US
dc.departmentMaltepe Üniversitesien_US
dc.description.abstractObjective: Gallbladder is one of the most commonly encountered specimen in a pathology laboratory. A diverse spectrum of diseases affect the biliary system, often presenting with similar clinical signs and symptoms. We aimed to define the profile of gallbladder diseases in our region, and to determine potential correlations between histopathologic features we observed. Material and Method: We reviewed all cholecystectomies processed in Department of Pathology of Afyon Kocatepe University Hospital between January 2000 and March 2008. Gross and histopathologic features of the specimens were reevaluated. Results: Among 1500 patients; 69.9% were women and 30.1% were men. We found out fourteen primary gallbladder carcinomas (0.93%) with adenocarcinomas being the most frequent type (78.57%). The rate of cholelithiasis was found as 89.9%. The most common type of gallstones was mixed cholesterol type gallstones with 67.5% followed by black pigment and brown pigment types as 23.83% and 5.89%, respectively. The association of metaplasia with dysplasia and also gallstones were statistically significant (p<0.001, p<0.005). The rate of the gallbladder polyps was 2.6% with the cholesterol polyps being the most common type (56.4%). Conclusion: Gallbladder diseases often present with similar clinical signs and symptoms and a surgical pathologist should be alert especially of precancerous lesions. With our results, we also conclude that elderly women with longstanding gallstone disease should undergo elective surgery even when no symptoms are present.en_US
dc.identifier.doi10.5146/tjpath.2010.01043
dc.identifier.endpage30en_US
dc.identifier.issn1018-5615
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-79551699970en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage23en_US
dc.identifier.trdizinid111619en_US
dc.identifier.urihttps://dx.doi.org/10.5146/tjpath.2010.01043
dc.identifier.urihttps://hdl.handle.net/20.500.12415/8550
dc.identifier.volume27en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoenen_US
dc.publisherFederation of Turkish Pathology Societiesen_US
dc.relation.ispartofTurk Patoloji Dergisi/Turkish Journal of Pathologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKY03671
dc.subjectCholecystectomyen_US
dc.subjectCholelithiasisen_US
dc.subjectGallbladder diseasesen_US
dc.subjectGallbladder neoplasmsen_US
dc.subjectPrecancerous conditionsen_US
dc.titleProfile of gallbladder diseases diagnosed at Afyon Kocatepe University: A retrospective studyen_US
dc.typeArticle
dspace.entity.typePublication

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