Design of the polyacrylonitrile-reduced graphene oxide nanocomposite-based non-enzymatic electrochemical biosensor for glucose detection

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dc.authoridBaytemir, Gülsen/0000-0002-1143-0730en_US
dc.authoridTaşaltın, Nevin/0000-0001-6788-1605en_US
dc.authoridKARAKUS, SELCAN/0000-0002-8368-4609en_US
dc.contributor.authorKarakuş, Selcan
dc.contributor.authorTaşaltın, Cihat
dc.contributor.authorGurol, Like
dc.contributor.authorBaytemir, Gülsen
dc.contributor.authorTaşaltın, Nevin
dc.date.accessioned2024-07-12T21:37:22Z
dc.date.available2024-07-12T21:37:22Z
dc.date.issued2022en_US
dc.department[Belirlenecek]en_US
dc.description.abstractWith the advantages of developed electronic devices, various biosensor applications have become attractive issues with excellent electrochemical performances against biomarkers and molecules in biomedical applications. In this study, novel polyacrylonitrile (PAN)-reduced graphene oxide (rGO) nanocomposite-based non-enzymatic electrochemical biosensors were prepared to investigate the detection performance of the glucose. The PAN-rGO nanocomposite-based biosensor detected glucose with a high sensitivity and stability due to enhanced redox mechanism arising from rGO additive. PAN-rGO nanocomposite-based biosensor detected glucose in (0.75-12) mM with a high sensitivity of 49 mu AmM-1 cm(-2) (2.5 times higher than PAN-based sensor). Concentration-response graphs correlating the non-enzymatic electrochemical signal to glucose concentration revealed a low limit of detection (LOD) of 0.6 mM within 1-min voltammetric cycle. The selectivity results confirmed a significant preferential response of the proposed PAN-rGO nanocomposite-based biosensor for glucose against possible interfering compounds. The proposed PAN-rGO nanocomposite-based biosensor has a great potential to be used as a nanostructured platform for detection of glucose in phosphate-buffered saline (pH 7.4) solution with high sensitivity, selectivity, stability, reproducibility, and fast response properties.en_US
dc.description.sponsorshipTUBITAK [216M421]en_US
dc.description.sponsorshipThis research was supported by TUBITAK Project 216M421.en_US
dc.identifier.doi10.1007/s10854-022-08694-9
dc.identifier.endpage18409en_US
dc.identifier.issn0957-4522
dc.identifier.issn1573-482X
dc.identifier.issue23en_US
dc.identifier.scopus2-s2.0-85134293057en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage18400en_US
dc.identifier.urihttps://doi.org/10.1007/s10854-022-08694-9
dc.identifier.urihttps://hdl.handle.net/20.500.12415/6765
dc.identifier.volume33en_US
dc.identifier.wosWOS:000825912400004en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofJournal of Materials Science-Materials in Electronicsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKY04107
dc.titleDesign of the polyacrylonitrile-reduced graphene oxide nanocomposite-based non-enzymatic electrochemical biosensor for glucose detectionen_US
dc.typeArticle
dspace.entity.typePublication

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