Bifidobacteria and Mucosal-Associated Invariant T (MAIT) Cells: A New Approach to Colorectal Cancer Prevention?

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dc.authoridBozkurt, Hüseyin S/0000-0003-2097-2950en_US
dc.contributor.authorBozkurt, Hüseyin Sancar
dc.contributor.authorQuigley, Eamonn M. M.
dc.date.accessioned2024-07-12T21:37:27Z
dc.date.available2024-07-12T21:37:27Z
dc.date.issued2019en_US
dc.department[Belirlenecek]en_US
dc.description.abstractColorectal cancer is the most preventable form of cancer worldwide. The pathogenesis of colorectal cancer includes gut inflammation, genetic and microbial composition factors. Impairment of the gut microbiota has been associated with development of colorectal cancer. The genus Bifidobacterium is an important component of the commensal gut microbiota. Bifidobacteria are considered to have important roles in multiple homeostatic functions: immunologic, hormonal and metabolic. Mucosal-associated invariant T cells (MAIT) are components of the immune system involved in protection against infectious pathogens and regulate the pathogenesis of various inflammatory diseases and, potentially, colorectal cancer. Engagement between Bifidobacterium and MAIT cells could exert a beneficial effect on colorectal cancer prevention and treatment.en_US
dc.identifier.doi10.3390/gidisord1020022
dc.identifier.endpage272en_US
dc.identifier.issn2624-5647
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85089435993en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage266en_US
dc.identifier.urihttps://doi.org/10.3390/gidisord1020022
dc.identifier.urihttps://hdl.handle.net/20.500.12415/6778
dc.identifier.volume1en_US
dc.identifier.wosWOS:000661733100001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherMdpien_US
dc.relation.ispartofGastrointestinal Disordersen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKY04120
dc.subjectBifidobacteriumen_US
dc.subjectMait Cellsen_US
dc.subjectColorectal Canceren_US
dc.titleBifidobacteria and Mucosal-Associated Invariant T (MAIT) Cells: A New Approach to Colorectal Cancer Prevention?en_US
dc.typeArticle
dspace.entity.typePublication

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