Carbetocin Versus Oxytocin for Prevention of Postpartum Hemorrhage in Cesarean Section

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dc.authoridGürsoy, Ali/0000-0001-7275-3800;en_US
dc.contributor.authorGürsoy, Ali
dc.contributor.authorIlter, Erdin
dc.contributor.authorÇelik, Aygen
dc.contributor.authorPeker, Berna Haliloğlu
dc.contributor.authorSerifsoy, Talat Ercan
dc.contributor.authorAtasayan, Kemal
dc.contributor.authorÖzekici, Umit
dc.date.accessioned2024-07-12T21:37:34Z
dc.date.available2024-07-12T21:37:34Z
dc.date.issued2021en_US
dc.department[Belirlenecek]en_US
dc.description.abstractObjective: We aimed to compare the haemodynamic effects of carbetocin and oxytocin in preventing postpartum hemorrhage during cesarean delivery. Material and Methods: This study was conducted retrospectively in a university hospital. Women in the carbetocin group (n=42) and women in the oxytocin group (n=78) were evaluated in terms of changes in hemoglobin level, hematocrit level, uterotonic need, urine output, blood transfusion requirement, hospital stay, postoperative fever and need for peripartum hysterectomy. Results: There was not statistically significant difference between their additional uterotonic need but preoperative and postoperative 24th hour hemoglobin reduction, calculated estimated blood loss and platelet count diminution percentage were significantly lower in the carbetocin group compared to oxytocin group (p=0.044; p=0.042; p=0.004, respectively). Besides that, the rate of blood loss of >= 500 mL was lower but not significantly different in patients receiving carbetocin compared to those using oxytocin (p=0.059) and the duration to reach 1,500 cc urine output of carbetocin group was significantly lower than the oxytocin group (p=0.001). Conclusion: Carbetocin appears to be more effective in the hemoglobin reduction, platelet reduction and calculated estimated blood loss. In addition, another advantage of carbetocin is that it has lower negative effects on urine output than oxytocin. It is noteworthy that carbetocin administration can prevent postpartum hemorrhage in appropriate cases.en_US
dc.identifier.doi10.5336/jcog.2020-79994
dc.identifier.endpage27en_US
dc.identifier.issn2619-9467
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85118629577en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage20en_US
dc.identifier.trdizinid413137en_US
dc.identifier.urihttps://doi.org/10.5336/jcog.2020-79994
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/413137
dc.identifier.urihttps://hdl.handle.net/20.500.12415/6849
dc.identifier.volume31en_US
dc.identifier.wosWOS:000871240900004en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoenen_US
dc.publisherTurkiye Kliniklerien_US
dc.relation.ispartofJournal of Clinical Obstetrics And Gynecologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKY04191
dc.subjectCarbetocinen_US
dc.subjectOxytocinen_US
dc.subjectPostpartum Hemorrhageen_US
dc.titleCarbetocin Versus Oxytocin for Prevention of Postpartum Hemorrhage in Cesarean Sectionen_US
dc.typeArticle
dspace.entity.typePublication

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