An approach for prediction of optimum reaction conditions for laccase-catalyzed bio-transformation of 1-naphthol by response surface methodology (RSM)

dc.authorid0000-0002-3537-6505en_US
dc.authorid0000-0001-9341-607Xen_US
dc.contributor.authorCeylan, Hasan
dc.contributor.authorKubilay, Şenol
dc.contributor.authorAktaş, Nahit
dc.contributor.authorŞahiner, Nurettin
dc.contributor.authorCeylan, Hasan
dc.date.accessioned2024-07-12T20:35:59Z
dc.date.available2024-07-12T20:35:59Z
dc.date.issued2008en_US
dc.departmentFakülteler, Eğitim Fakültesi, İlköğretim Matematik Öğretmenliği Bölümüen_US
dc.description.abstractResponse surface methodology (RSM) was successfully applied to enzymatic bio-transformation of 1-naphthol. The experiments were conducted in a closed system containing acetone and sodium acetate buffer, with laccase enzyme. Laccase enzyme used as catalyst was derived from Trametes versicolor (ATCC 200801). The enzymatic bio-transformation rate of 1-naphthol, based on measurements of initial dissolved oxygen (DO) consumption rate in the closed system, was optimized by the application of RSM. The independent variables, which had been found as the most effective variables on the initial DO consumption rate by screening experiments, were determined as medium temperature, pH and acetone content. A quadratic model was developed through RSM in terms of related independent variables to describe the DO consumption rate as the response. Based on contour plots and variance analysis, optimum operational conditions for maximizing initial DO consumption rate, while keeping acetone content at its minimum value, were 301 K of temperature, pH 6 and acetone content of 7% to obtain 9.17 · 10 3 mM DO/min for initial oxidation rate.en_US
dc.identifier.citationCeylan, H., Kubilay, Ş., Aktaş, N. ve Şahiner, N. (2008). An approach for prediction of optimum reaction conditions for laccase-catalyzed bio-transformation of 1-naphthol by response surface methodology (RSM). Bioresource Technology. 99(6), s. 2025-2031.en_US
dc.identifier.endpage2031en_US
dc.identifier.issn0960-8524
dc.identifier.issue6en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage2025en_US
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0960852407002520
dc.identifier.urihttps://hdl.handle.net/20.500.12415/998
dc.identifier.volume99en_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofBioresource Technologyen_US
dc.relation.isversionof10.1016/j.biortech.2007.03.018en_US
dc.relation.publicationcategoryUluslararası Hakemli Dergide Makale - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKY00426
dc.subjectLaccaseen_US
dc.subject1-Naphtholen_US
dc.subjectEnzymatic polymerizationen_US
dc.subjectResponse surface methodologyen_US
dc.subjectOptimizationen_US
dc.titleAn approach for prediction of optimum reaction conditions for laccase-catalyzed bio-transformation of 1-naphthol by response surface methodology (RSM)en_US
dc.typeArticle
dspace.entity.typePublication

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