Can complete blood count parameters be a good marker for substance use disorder?

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dc.authoridKök Kendirlioğlu, Burcu/0000-0003-0632-1617en_US
dc.authoridBüyüksandalyacı Tunç, Ece/0000-0002-6358-4643en_US
dc.contributor.authorArat Çelik, Hidayet Ece
dc.contributor.authorKendirlioğlu, Burcu Kok
dc.contributor.authorTunç, Ayşe Ece Büyüksandalyacı
dc.contributor.authorÇörekli, Esma
dc.contributor.authorDemir, Sevin
dc.contributor.authorKucukgoncu, Suat
dc.date.accessioned2024-07-12T21:37:42Z
dc.date.available2024-07-12T21:37:42Z
dc.date.issued2023en_US
dc.department[Belirlenecek]en_US
dc.description.abstractObjectiveInflamatory processes play an important role in the etiology of psychiatric disorders. The aim of this study was to evaluate inflammatory complete blood count (CBC) parameters in substance use disorder (SUD).MethodsThe study included 90 patients with SUD and 90 healthy controls (HC). The Student t-test was used to compare CBC parameters between the groups. The Kruskal - Wallis test was used to compare the data on the basis of substance types.ResultsLeukocyte, lymphocyte, and monocyte levels were higher in SUD group than HC. Leukocyte and neutrophil levels of patients with opioid use disorder (OUD) were higher than HC. Platelet levels and neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and systemic immune inflammation index values were higher in patients with OUD than in patients with non-opioid substance use disorder (nOUD). Moreover, lymphocyte and monocyte levels were higher in patients with nOUD than in HC. Monocyte levels were increased in patients with cannabinoid use disorder compared to HC.ConclusionThe results suggested that inflammatory CBC parameters play an important role in the etiology of SUD according to type of substance. However, there is not enough data for supporting the clinical use of these parameters..en_US
dc.identifier.doi10.1080/14659891.2023.2213321
dc.identifier.issn1465-9891
dc.identifier.issn1475-9942
dc.identifier.scopus2-s2.0-85159310910en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.urihttps://doi.org/10.1080/14659891.2023.2213321
dc.identifier.urihttps://hdl.handle.net/20.500.12415/6892
dc.identifier.wosWOS:000987104900001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherTaylor & Francis Incen_US
dc.relation.ispartofJournal of Substance Useen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKY04234
dc.subjectComplete Blood Count Parametersen_US
dc.subjectMonocyte-To-Lymphocyte Ratioen_US
dc.subjectNeutrophil-To-Lymphocyte Ratioen_US
dc.subjectPlatelet-To-Lymphocyte Ratioen_US
dc.subjectSubstance Use Disorderen_US
dc.titleCan complete blood count parameters be a good marker for substance use disorder?en_US
dc.typeArticle
dspace.entity.typePublication

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