Diagnostic Value of Non-specific Clinical and Laboratory Findings in Patients Suspected of Crimean-Congo Hemorrhagic Fever in an Endemic Region

dc.authoridHamidi, Aziz Ahmad/0000-0003-4108-0847en_US
dc.contributor.authorHamidi, Aziz Ahmad
dc.contributor.authorKescioğlu, Serhat
dc.date.accessioned2024-07-12T21:37:34Z
dc.date.available2024-07-12T21:37:34Z
dc.date.issued2021en_US
dc.department[Belirlenecek]en_US
dc.description.abstractBackground: We aimed to determine diagnostic sensitivity and specificity of clinical and laboratory findings in patients with Crimean-Congo hemorrhagic fever (CCHF).Methods: We retrospectively reviewed the characteristics of patients who were suspected of CCHF. The patients were stratified into two groups as positive and negative based on results of CCHF specific IgM and viral RNA by real-time polymerase chain reaction (RT-PCR).Results: Mean age of 125 patients included (55.2% women, 44.8% men) was 47 +/- 20 years. The highest sensitivity (95%) was in myalgia. When the association of multiple findings were assessed, the highest sensitivity was found for myalgia plus transaminase elevation (Odds ratio [OR] 9.3; 95% confidence interval [CI] 3.75-23.05; p<0.05). The highest specificity was found for myalgia plus history of husbandry plus transaminase elevation (OR 15; 95% CI 5.27-42.68; p<0.05).Conclusion: If patients have myalgia and transaminase elevation with a history of husbandry at endemic regions, CCHF should be considered.en_US
dc.identifier.doi10.36519/idcm.2021.91
dc.identifier.endpage151en_US
dc.identifier.issn2667-646X
dc.identifier.issue3en_US
dc.identifier.startpage145en_US
dc.identifier.trdizinid506424en_US
dc.identifier.urihttps://doi.org/10.36519/idcm.2021.91
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/506424
dc.identifier.urihttps://hdl.handle.net/20.500.12415/6853
dc.identifier.volume3en_US
dc.identifier.wosWOS:001085202900006en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakTR-Dizin
dc.language.isoenen_US
dc.publisherDoc Design Informatics Co Ltden_US
dc.relation.ispartofInfectious Diseases And Clinical Microbiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKY04195
dc.subjectCrimean -Congo Hemorrhagic Feveren_US
dc.subjectThrombocytopeniaen_US
dc.subjectHemorrhagic Feveren_US
dc.subjectTicken_US
dc.subjectExposureen_US
dc.subjectDiagnostic Valueen_US
dc.titleDiagnostic Value of Non-specific Clinical and Laboratory Findings in Patients Suspected of Crimean-Congo Hemorrhagic Fever in an Endemic Regionen_US
dc.typeArticle
dspace.entity.typePublication

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