Effectiveness of glucose-insulin-potassium treatment in nondiabetic patients with acute myocardial infarction

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dc.contributor.authorKeskin, F. E.
dc.contributor.authorÇelebi, Aslan
dc.contributor.authorKeskin, Serkan
dc.contributor.authorSayali, Erhan
dc.contributor.authorGurol, Tayfun
dc.contributor.authorAlicanoğlu, Riza
dc.contributor.authorKoc, Deniz Ogutmen
dc.date.accessioned2024-07-12T21:38:01Z
dc.date.available2024-07-12T21:38:01Z
dc.date.issued2008en_US
dc.department[Belirlenecek]en_US
dc.description.abstractObjective: Glucose-insulin-potassium (GIK) treatment given additional to standard therapy effectiveness was investigated in nondiabetic patients with acute myocardial infarction. Material and Method: 29 nondiabetic patients with acute myocardial infarction participated between January and June 2005 in Taksim Training and Research Hospital Coronary Care Unit. Besides standard therapy 14 patients received GIK solution while 15 patients did not. The cardiac enzyme increasing velocity differences were investigated. All patients investigated were nondiabetics. Myocardial infarction was diagnosed by chest pain, electrocardiography and cardiac enzyme assessments. Blood samples for creatin phosphokinase, CPK-MB, myoglobine, Troponin-I and C-reactive protein (CRP) were enrolled at index and further after 6th, 12th and 24th hours. Results: No difference was detected regarding age, body weight, height, application time and lipid profiles between two groups. Although index of 6th and 12th hour controls showed no difference, 24th hour values showed statistically significant difference with a p=0.0013. CRP level in GIK group was 22.56 +/- 12.95 mg/dL and 78.92 +/- 69.94 mg/dL in non-GIK group. In our assessment using DUNN's multiple comparison test, although in the group receiving GIK, there was a statistically significant difference accordingly Troponin-I initial and 6th, 12th hours; there was no difference in the given GIK and non GIK group. In comparison of the CRP levels at index and at 24th hour p values were found less than 0,05 (p<0,05) in both groups. Conclusion: In our study, we realized that in the group given GIK; some of the myocardial injury markers were decreasing and finally decided that GIK solution could be beneficial in diabetic and nondiabetic patients.en_US
dc.identifier.endpage64en_US
dc.identifier.issn1305-9319
dc.identifier.issn1305-9327
dc.identifier.issue2en_US
dc.identifier.startpage58en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12415/7034
dc.identifier.volume4en_US
dc.identifier.wosWOS:000420488500004en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Science
dc.language.isotren_US
dc.publisherYerkure Tanitim & Yayincilik Hizmetleri A Sen_US
dc.relation.ispartofMedical Journal of Bakirkoyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKY04406
dc.subjectMyocardial Infarctionen_US
dc.subjectGlucoseen_US
dc.subjectInsulinen_US
dc.subjectPotassiumen_US
dc.titleEffectiveness of glucose-insulin-potassium treatment in nondiabetic patients with acute myocardial infarctionen_US
dc.typeArticle
dspace.entity.typePublication

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