Assessment of Probe-to-Specimen Distance Effect in Kidney Stone Treatment With Hydrodynamic Cavitation

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dc.authorid0000-0001-7739-2346en_US
dc.authorid0000-0001-6283-6717en_US
dc.contributor.authorUzusen, Dogan
dc.contributor.authorDemir, Ebru
dc.contributor.authorPerk, Osman Yavuz
dc.contributor.authorOral, Ozlem
dc.contributor.authorEkici, Sinan
dc.contributor.authorUnel, Mustafa
dc.contributor.authorGozuacik, Devrim
dc.contributor.authorKosar, Ali
dc.date.accessioned2024-07-12T21:50:58Z
dc.date.available2024-07-12T21:50:58Z
dc.date.issued2015en_US
dc.departmentMaltepe Üniversitesien_US
dc.description.abstractThe aim of this study is to focus on the effect of probe-to-specimen distance in kidney stone treatment with hydrodynamic bubbly cavitation. Cavitating bubbles were generated by running phosphate buffered saline (PBS) through stainless steel tubing of inner diameter of 1.56 mm at an inlet pressure of similar to 10,000 kPa, which was connected to a 0.75 mm long probe with an inner diameter of 147 mu m at the exit providing a sudden contraction and thus low local pressures. The bubbles were targeted on the surface of nine calcium oxalate kidney stones (submerged in a water pool at room temperature and atmospheric pressure) from three different distances, namely, 0.5 mm, 2.75 mm, and 7.75 mm. The experiments were repeated for three different time durations (5 min, 10 min, and 20 min). The experimental data show that amongst the three distances considered, the distance of 2.75 mm results in the highest erosion amount and highest erosion rate (up to 0.94 mg/min), which suggests that a closer distance does not necessarily lead to a higher erosion rate and that the probe-to-specimen distance is a factor of great importance, which needs to be optimized. In order to be able to explain the experimental results, a visualization study was also conducted with a high speed CMOS camera. A new correlation was developed to predict the erosion rates on kidney stones exposed to hydrodynamic cavitation as a function of material properties, time, and distance.en_US
dc.description.sponsorshipSabanci University Internal Grant for Research Program [IACF09-00642]; TUBITAK (The Scientific and Technological Research Council of Turkey) Support Program for Scientific and Technological Research Projects [111M621, 113S092]; Sabanci University Internal Grant for Research Program [IACF09-00642]; TUBITAK (The Scientific and Technological Research Council of Turkey) Support Program for Scientific and Technological Research Projects [111M621, 113S092]en_US
dc.description.sponsorshipThis work was supported by Sabanci University Internal Grant for Research Program under Grant Nos. IACF09-00642 and TUBITAK (The Scientific and Technological Research Council of Turkey) Support Program for Scientific and Technological Research Projects Grant Nos. 111M621 and 113S092. Undergraduate and graduate student support from Faculty of Engineering and Natural Sciences of Sabanci University and equipment utilization support from Sabanci University Nanotechnology Research and Applications Center (SUNUM) was also gratefully appreciated.en_US
dc.identifier.doi10.1115/1.4030274
dc.identifier.issn1932-6181
dc.identifier.issn1932-619X
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-84937597582en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.urihttps://dx.doi.org/10.1115/1.4030274
dc.identifier.urihttps://hdl.handle.net/20.500.12415/8227
dc.identifier.volume9en_US
dc.identifier.wosWOS:000370684800056en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherASMEen_US
dc.relation.ispartofJOURNAL OF MEDICAL DEVICES-TRANSACTIONS OF THE ASMEen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKY01970
dc.titleAssessment of Probe-to-Specimen Distance Effect in Kidney Stone Treatment With Hydrodynamic Cavitationen_US
dc.typeArticle
dspace.entity.typePublication

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