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    Breast cancer in association with thyroid disorders
    (Biomedcentral, 2003) Narin, Y.; Demirbaş, S.; Önde, M.E.; Sayan, Ö.; Kandemir, E.G.; Yaylacı, M.; Öztürk, A.
    Breast cancer is a hormone-dependent neoplasm. Conflicting results regarding the clinical correlation between breast cancer and thyroid diseases have been reported in the literature. Many studies showed that thyroid diseases are common among women with breast cancer [1–6], whereas other reports did not confirm such an association of breast cancer with thyroid diseases [7–11]. Almost every form of thyroid disease, including nodular hyperplasia [12], hyperthyroidism [13] and thyroid cancer [14, 15], has been identified in association with breast cancer. These findings have led to the investigation of the relationship between breast cancer and autoimmune thyroid diseases (AITDs). Such a relationship is not a new observation, and some authors have reported a higher prevalance of AITDs among breast cancer patients than in age-matched control individuals [16–18]. The precise significance of this association remains elusive, and some reports have shown that the presence of thyroid peroxidase (TPO) antibodies is associated with a significant improvement in outcome among breast cancer patients [19] and is of similar importance to other prognostic indices such as axillary nodal status and tumour size [20]. The aim of the present prospective study was to determine the prevalence of thyroid diseases in patients with breast cancer as compared with that in the general female population.