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    Hemorrhagic Age-Related Macular Degeneration Managed With Vitrectomy, Subretinal Injection of Tissue Plasminogen Activator, Gas Tamponade, and Upright Positioning
    (SLACK INC, 2013) Kapran, Ziya; Ozkaya, Abdullah; Uyar, O. Murat
    BACKGROUND AND OBJECTIVE: To investigate the outcomes of vitrectomy, subretinal tissue plasminogen (tPA) injection, gas tamponade, and upright positioning in patients with hemorrhagic neovascular age-related macular degeneration (AMD). PATIENTS AND METHODS: Retrospective, noncomparative case series. Records of patients who were diagnosed with submacular hemorrhage secondary to neovascular AMD and underwent treatment with the combined method between 2004 and 2010 were reviewed. The main outcome measure was the difference between preoperative and postoperative best corrected visual acuity (BCVA). RESULTS: In 10 eyes of 10 patients, mean preoperative and postoperative BCVA values were 1.75 and 1.23 logMAR, respectively (P = .011), after a mean follow-up time of 38.7 +/- 26.5 months (range: 10 to 71 months). Eight of 10 patients (80%) gained at least three lines. CONCLUSION: In patients with hemorrhagic neovascular AMD, treatment with vitrectomy, subretinal tPA injection, gas tamponade, and upright positioning was associated with better visual outcomes than those reported for patients with untreated disease.
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    Wide-Field Landers Keratoprothesis in Various Combined Corneal and Vitreoretinal Problems: Twelve-Month Results
    (SLACK INC, 2017) Kapran, Ziya; Ozkaya, Abdullah; Erdogan, Gurkan; Karakucuk, Yalcin; Gezginaslan, Tugba Aydogan; Perente, Irfan; Taskapili, Muhittin
    BACKGROUND AND OBJECTIVE: To investigate the outcomes of combined pars plana vitrectomy (PPV), transient keratoprosthesis (TKP), and penetrating keratoplasty (PKP) in patients with coexisting corneal and vitreoretinal diseases. PATIENTS AND METHODS: Patients who underwent PPV, TKP, and PKP were included. The main outcome measures were change in visual acuity (VA), clarity of the graft, and retinal attachment. RESULTS: Twenty eyes were included. The mean follow-up time was 18 months +/- 9.5 months. The baseline VA was light perception in 15 eyes and hand motions in five eyes and was found to be increased in 15 eyes (75%), decreased in one eye (5%), and stable in four eyes (20%). The mean corneal graft survival time was 11.1 months +/- 8.5 months. Three eyes (15%) showed phthisis bulbi at the last visit. CONCLUSION: The triple procedure seems to be an effective treatment option in patients who suffer from coexisting corneal and vitreoretinal diseases.