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    Associations between stages of diabetic polyneuropathy and quality of life, neuropathic pain, and well-being: A multicenter, cross-sectional analysis based on electroneuromyographic findings
    (Elsevier, 2024) Kılıçparlar Cengiz, Emine; Ekmekyapar Fırat, Yasemin; Karşıdağ, Sibel; Neyal, Abdurrahman; Erdemoglu, Ali Kemal; Çınar, Nilgün; Ekmekyapar, Tuba; Canbaz Kabay, Sibel; Akkoyun Arıkan, Fatma; Akdağ, Gonül; Çomruk, Gülsüm; Ates, Miruna; Kendirli Aslan, Sude; Çokal, Burcu Gökçe; Tosunoglu, Bünyamin; Bolu, Naci Emre; Yanık, Ece; Savrun, Feray; Tülek, Zeliha; Kılıçaslan, Kimya; Çakar, Egemen Kaan; Ergin Bakar, Ebru; Atmaca, Murat Mert; Yılmaz, Buket; Neyal, Ayşe Münife
    Aim: This study aimed to investigate the relationship between electrophysiological findings of diabetic neu ropathy (DN) and patients’ quality of life, neuropathic pain levels, and well-being. Materials and Methods: A cross-sectional study was conducted in 12 centers in Turkey. DN patients were cate gorized into four stages based on electrophysiological findings using the Baba classification. Scales such as Short Form-36 (SF-36), Douleur Neuropathique 4-Questions (DN4), Brief Pain Inventory (BPI), and WHO-5 Well-Being (WHO-5 WB) were used to assess quality of life, pain, and well-being. Additional factors like HbA1c levels and diabetes duration were analyzed. Results: Among 323 DN patients, 90 were in stage 1, 84 in stage 2, 72 in stage 3, and 77 in stage 4. There were no significant differences in age or gender between the stages. Diabetes duration and HbA1c levels were signifi cantly lower in stage 1 compared to later stages. SF-36 and WHO-5 WB scores declined, while DN4 and BPI pain interference scores increased in the later stages. These findings persisted after adjusting for confounders such as age, BMI, comorbidities, and diabetes duration. Conclusion: Patients with advanced-stage DN experienced a poorer quality of life, greater pain, and more frequent comorbidities compared to early-stage patients. Electrophysiological findings should be considered in the clinical management of DN.
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    The Impact of the COVID-19 Lockdown on the Quality of Life in Chronic Neurological Diseases: The Results of a COVQoL-CND Study
    (Karger, 2021) Şahin, Şevki; Karşıdağ, Sibel; Çınar, Nilgün; Ates, Miruna Florentina; Demir, Serkan; Eren, Fettah; Neyal, Abdurrahman
    Background: Coronavirus disease 2019 (COVID-19) pandemic and lockdown period may induce an impairment in quality of life (QoL), disruption in treatment (DIT), and posttraumatic stress disorder (PTSD) in chronic neurological diseases (CNDs). To reach this information, a multicenter, cross-sectional study (COVQoL-CND) was planned. Parkinson's disease (PD), headache (HA), multiple sclerosis (MS), epilepsy (EP), polyneuropathy (PNP), and cerebrovascular disease (CVD) were selected as the CND. Methods: The COVQoL-CND study includes demographic data, the World Health Organization Quality of Life short form (WHOQOL-BREF), and Impact of Event Scale-Revised (IES-R) forms. Results: The mean age of a total of 577 patients was 49 +/- 17 (19-87 years), and the ratio of female/male was 352/225. The mean age of patients with PD, HA, MS, EP, PNP, and CVD were 65 +/- 11, 39 +/- 12, 38 +/- 10, 47 +/- 17, 61 +/- 12, and 60 +/- 15 years, respectively. The IES-R scores were found to be higher in the younger group, those with comorbid disease, contacted with CO-VID-19 patients, or diagnosed with COVID-19. In the group with a high IES-R score, the rate of DIT was found to be high. IES-R scores were negatively correlated with QoL. IES-R total scores were found highest in the CVD group and lowest in the PD group. The ratio of DIT was found highest in the PNP group and the lowest in the EP group. Contact with CO-VID-19 patients was high in the EP and HA group. Conclusions: The results of the COVQoL-CND study showed that lockdown causes posttraumatic stress and deterioration in the QoL in CND.