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    Comparison of the sixth and seventh editions of the TNM staging systems with regard to non-small cell lung carcinoma
    (BAYCINAR MEDICAL PUBL-BAYCINAR TIBBI YAYINCILIK, 2012) Duzgun, Yeliz; Saygi, Attila; Levent, Ender; Yilmaz, Huri Ozkan; Koksal, Hulya; Soylu, Akin Cem; Kutlu, Cemal Asim
    Background: In this study, we aimed to compare the clinical tumor node metastasis (TNM) and pathological TNM staging of non-small cell lung cancer (NSCLC) using the sixth and seventh editions of the TNM staging and to establish whether there was any concordance between these editions. Methods: The records of 60 patients (57 males, 3 females; mean age 57 10 years; range 34 to 81 years) who were operated between January 2007 and October 2009 diagnosed with NSCLC in our clinic were retrospectively analyzed. Both clinical (pre-thoracotomy) and pathological (post-thoracotomy) staging were performed separately according to the sixth and seventh editions of the TNM systems. Results: With the sixth edition, the concordance rate for the clinical and pathological T stage was 73.3% while the concordance rate for the clinical TNM and pathological TNM stage was 48.3%. Twenty percent of the patients were clinically underestimated, and 31.7% were overestimated. The seventh edition of the TNM staging yielded concordance rates of 61.7% for the clinical and pathological T stage and 41.7% for the clinical TNM and pathological TNM stage was 41.7%. With this edition, 28.3% of the patients were clinically underestimated, and 30% were overestimated. Clinical and pathological TNM staging according to seventh edition were similar to the previous stages in 81.7% and 70% of the patients, respectively while understaging was seen in 6.7% and 5.0%, respectively. Overstaging occurred in 11.7% and 25.0% of the patients, respectively. Conclusion: In our study, the concordance rate for the clinical TNM and pathological TNM stage was lower for the seventh edition of the staging systems than for the sixth editon. This result suggests the importance of invasive staging and systematic lymph node dissection. Based on our samples with early stage, we believe that there should be no change in the treatment for patients with upstaging according to the seventh edition of the staging system.
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    Malignant Invasive Thymoma in the Posterior Mediastinum
    (ELSEVIER SCIENCE INC, 2009) Orki, Alpay; Patlakoglu, Mehmet Suat; Tahaoglu, Canan; Kutlu, Cemal Asim
    We present a rare case of malignant invasive thymoma (type A) arising from the posterior mediastinum. A 17-year-old girl was referred to our clinic after detection of a mass on a chest roentgenogram. Thoracoscopy showed a lobulated, pale yellowish mass located in the posterior compartment together with several foci in the lung parenchyma. The tumor and parenchymal foci were totally resected through a left minithoracotomy. Postoperative pathology revealed malignant invasive thymoma type A.
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    Video-assisted Thoracoscopy for Spontaneous Pneumothorax after Pneumonectomy
    (ELSEVIER SCIENCE INC, 2009) Orki, Alpay; Tasci, Ahmet Erdal; Meydan, Burhan; Kutlu, Cemal Asim
    In this paper, we present 3 patients who had previously undergone pneumonectomy and then presented with a spontaneous pneumothorax. The indication for pneumonectomy was tuberculosis and NSCLC in 2 and 1 patient, respectively. The interval between the surgery and development of pneumothorax was 2, 4, and 11 years. On admission, 2 of the 3 patients were in extreme respiratory distress requiring urgent chest tube insertion. In all patients we undertook elective video-assisted thoracoscopy with complete preparation for cardiopulmonary support on the side. Bullectorny and/or diathermy ablation for apical bullae and blebs were performed concomitantly with total parietal pleurectomy. The postoperative course was uneventful in the patients, and they remain on routine follow-up for up to 6-12 months without any complaints. Our experience suggests that emphysematous changes in the remaining lung should be carefully inspected during long-term follow-up after pneumonectomy. Video-assisted thoracoscopic (VAT) pleurectomy appears to be a good option for the management of spontaneous pneumothorax only if it is performed by a dedicated multidisciplinary team with various cardiopulmonary support facilities on the side. (Heart, Lung and Circulation 2009;18:296-312) (c) 2008 Australasian Society of Cardiac and Thoracic Surgeons and the Cardiac Society of Australia and New Zealand. Published by Elsevier Inc. All rights reserved.