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    Can high volume pericapsular nerve group (PENG) block act as a lumbar plexus block?
    (ELSEVIER SCIENCE INC, 2020) Alasehir, Elcin Akduman; Ipek, Belkiz Ongen; Thomas, David Terence; Ercan, Tugba Erener; Sitar, Mustafa Erinc
    Can high volume pericapsular nerve group (PENG) block act as a lumbar plexus block?
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    The Effects of Initial Procalcitonin Levels on Mortality Rates in Geriatric Patients Undergoing Surgery
    (CUREUS INC, 2020) Ipek, Belkiz Ongen; Karadeniz, Asli; Sitar, Mustafa Erinc
    Introduction The aim of the current study is to investigate the relationship between mortality rate in geriatric patients undergoing surgery with preoperative serum levels of procalcitonin, C-reactive protein, and erythrocyte sedimentation rate. Methods This was a single-center retrospective study, including three groups with 101 patients, who are older than 65 years of age. A retrospective investigation was carried out from the laboratory information system for all groups from January to December 2018. Group 1 included patients who had surgery and then mortality within 30 days after surgery. Group 2 included hospitalized patients who had surgery and no mortality within 30 days after surgery. Group 3 included outpatient patients, who had suspicion for a bacterial infection and then no surgery or no mortality within 30 days. Results When three group comparisons were made for procalcitonin, C-reactive protein, and erythrocyte sedimentation rate values, the p-value of one-way analysis of variance (ANOVA) was higher than 0.05 for procalcitonin and lower than 0.05 for C-reactive protein and erythrocyte sedimentation rate, suggesting that one or more groups were significantly different. When post-hoc multiple comparison methods were applied, there were statistically significant differences between Groups 1 and 3 for C-reactive protein and erythrocyte sedimentation rate. Conclusions Procalcitonin levels do not predict mortality following surgery. C-reactive protein and erythrocyte sedimentation rate are more useful biomarkers predicting mortality in geriatric patients undergoing surgery.
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    Idiopathic chylothorax in geriatrics: the oldest case report so far
    (WALTER DE GRUYTER GMBH, 2018) Ipek, Belkiz Ongen; Alasehir, Elcin Akduman; Sitar, Mustafa Erinc; Levent, Ender; Orki, Alpay
    Chylothorax is a rare condition characterized by accumulation of chylous fluid in the pleural space resulting in impaired ductus thoracic integrity. It can be an outcome of a traumatic process, although there are a few non-traumatic and/or idiopathic cases in current literature. In this article, we present the oldest case report so for, who is an 87-year-old woman complaining of acute respiratory distress symptoms with pleural effusion having no trauma history. The patient was analyzed for the disease etiology strenuously. Thoracentesis was performed together with imaging modalities and detailed systemic laboratory tests. Non-surgical treatment was successful as the outcome.
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    Morphological and biomechanical effects of vitamin K2 on fracture healing: An animal study on the rat tibia fracture model
    (Turkish Assoc Orthopaedics Traumatology, 2023) Ünal, Ömer Kays; Dağtaş, Mirza Zafer; Ipek, Belkiz Ongen; Sitar, Mustafa Erinc; Ugutmen, Ender
    Objective: The aim of this study was to evaluate the effects of vitamin K2 on fracture healing.Methods: Twenty-four 6-week-old male Wistar albino rats that had open tibia fractures induced were included in this study. They were divided into 2 groups of 12, a group that had vitamin K2 administered over 30 consecutive days and a control group. After 30 days, the rats were sacrificed, and from each group, 6 tibiae were selected for biomechanical testing to examine the mechanical strength of the callus tissue using the Instron 3-point bending test and 6 tibiae were selected for histological analysis to examine the density and organization of callus tissue using Allen's grading system and Huo et al's grading system. Furthermore, weekly x-rays were taken to evaluate bone union described by Lane and Sandhu, and osteocalcin, procollagen I N-terminal propeptide, and procollagen I C-terminal propeptide were examined in blood samples taken by intracardiac puncture during sacrification.Results: Breaking force (P = .047), breaking time (P = .019), stiffness (P = .039), fracture strength (P = .041), and Young's modulus (P = .032) showed a statistically significant increase in the K2 group. Procollagen I C-terminal propeptide (P = .024), procollagen I N-terminal propep -tide (.047), and osteocalcin (.048) levels were significantly higher in the K2 group compared to the control group. Furthermore, 3rd-week x-rays showed higher bone union scores according to the Lane and Sandhu method in the K2 group (P = .014). However, the histological grading systems of Allen and Huo et al did not show statistically significant differences between groups (P = .086, P = .07, respectively).Conclusion: In light of these findings, it could be concluded that vitamin K2 has a significant positive effect on fracture healing.