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    An 11-month-old Girl with High Fever
    (SLACK INC, 2009) Ercan, Tugba Erener; Ercan, Gokmen; Arpaozu, Muhsin
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    Adenovirus and Rotavirus in Children with Acute Gastroenteritis
    (Aves Yayincilik, Ibrahim Kara, 2007) Akıncı, Nurver; Ercan, Tuğba Erener; Yalman, Nevin; Eren, Aynur; Severge, Burcu; Ercan, Gokmen
    Aim: Infectious diarrhea is one of the most important causes of mortality during childhood period in our country. Little is known about the epidemiology of rotavirus and adenovirus infections in Turkey. With this study, we aimed to determine the incidence of rotavirus and enteric adenovirus gastroenteritis in patients admitted to our pediatrics outpatient clinic. Material and Method: Stool specimens of 307 cases, who admitted to our pediatrics outpatient clinic during April 2004 and March 2005 due to diarrhea, were analyzed. Group A rotavirus and adenovirus serotype 40-41 were investigated in the stool specimens with the immunochromatographic test. Results: In 113 of the 307 stool specimens, viral antigens were determined. Of these 113 specimens, adenovirus was identified in 14.9 %, rotavirus in 13.7 %, both rotavirus and adenovirus in 8.2 %. Viral gastroenteritis cases were mostly seen during early spring and winter. The incidence of dehydration was significantly more common in rotavirus cases. Conclusion: Although rotavirus is the most common etiologic agent in viral gastroenteritis, rate of adenoviral gastroenteritis was comparable to that of rotavirus in our study. So, it is advisable to look also for adenovirus antigens since enteric adenoviruses have been recognized as an important cause of gastroenteritis in children.
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    Mycoplasma pneumoniae infection & obsessive-compulsive disease: A case report
    (SAGE PUBLICATIONS INC, 2008) Ercan, Tugba Erener; Ercan, Gokmen; Severge, Burcu; Arpaozu, Muhsin; Karasu, Gulten
    It has been demonstrated that obsessive-compulsive disease and/or tic syndromes in children may be triggered by an antecedent infection especially with group A beta-hemolytic streptococci, and this subgroup of children has been designated by the acronym PANDAS (pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections). Other infectious agents such as viruses and bacteria have also been reported to be associated with the acute onset or dramatic exacerbation of obsessive-compulsive disease or Tourette syndrome, and another acronym, PITAND (pediatric infection-triggered autoimmune neuropsychiatric disorder) has appeared in the literature. The involvement of other infectious agents such as Mycoplasma pneumoniae has been described in single case reports. We describe a case of a 5.5-year-old boy who suddenly developed obsessive-compulsive disease symptoms during a M. pneumoniae pneumonia. After treatment with oral clarithromycin, all his obsessive-compulsive disease symptoms disappeared. To our knowledge, this is the first report that shows the association between Mycoplasnw pneumoniae infection and obsessive-compulsive disease.
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    Tetanus and diphtheria immunity among term and preterm infant-mother pairs in Turkey, a country where maternal and neonatal tetanus have recently been eliminated
    (SPRINGER, 2015) Erener-Ercan, Tugba; Aslan, Mustafa; Vural, Mehmet; Erginoz, Ethem; Kocazeybek, Bekir; Ercan, Gokmen; Turkgeldi, Lale Wetherilt; Perk, Yildiz
    The aim of our study was to investigate the anti-tetanus and anti-diphtheria antibody titres and the placental transfer of these antibodies in a group of vaccinated and unvaccinated mothers and their term or preterm offsprings. Anti-tetanus and anti-diphtheria toxoid IgG antibodies were measured quantitatively by ELISA in 91 infant-mother pairs. Protective concentrations of anti-tetanus and anti-diphtheria were found in 58.3 and 50 % of mothers in the unvaccinated group and 94.5 and 85.5 % of the mothers in the vaccinated group. Protective concentrations were found in 63.9 and 50 % of cord samples, respectively, in the unvaccinated group and in 96.4 and 85.5 % of cord samples, respectively, in the vaccinated group (p = 0.0001). There were no differences in the maternal and cord geometric mean concentrations (GMCs) of anti-toxoid antibodies between those who received two doses or one dose of Td. The GMCs of maternal and cord anti-tetanus and anti-diphtheria were statistically similar between preterm and term groups. Placental transfer ratios (TR) for anti-tetanus and anti-diphtheria were 175 and 150 %, respectively, in the preterm group and 213 and 178 %, respectively, in the term group. There was a strong correlation between maternal and cord anti-toxoid antibody levels. Maternal vaccination was the only predictor of having protective concentrations of anti-toxoid antibodies in cord blood. Conclusions: Vaccinating pregnant women with at least one dose of Td would confer protection for both the term and preterm infant-mother pairs. Therefore, health personnel caring for pregnant women have the responsibility to emphasize the importance of Td vaccination to avoid missed immunization opportunities.