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Yayın Are neutrophil, platelet and eosinophil-to-lymphocyte ratio and red blood cell distribution width can be used for nasal polyposis?(Springerlink, 2017) Kara, Ahmet; Güven, Mehmet; Yılmaz, Mahmut Sinan; Demir, Deniz; Elden, Halil; Demir, DenizIntroduction The aim of this study is to explore the relationship of neutrophil, platelet and eosinophil-to-lymphocyte ratios and red blood cell distribution width values with nasal polyposis, and whether this could be a predictive parameter that can be used for the severity and recurrence risk of the disease. Method Neutrophil/lymphocyte, platelet/lymphocyte, eosinophil/lymphocyte ratios and red blood cell distribution width values were compared between nasal polyposis patients who were reviewed in a retrospective manner and the control group comparable for age and sex. Moreover, the nasal polyposis group was grouped for nasal polyposis severity and recurrence, and these subgroups were statistically compared, too. Results When the nasal polyposis patient group and the control group are compared, no statistically significant difference was found between two groups except for eosinophil/lymphocyte ratio. While only the difference between nasal polyposis severity and eosinophil/lymphocyte ratio is statistically significant, there was no parameter with statistically significant difference for recurrence. Conclusion We think that caution should be exercised when using these new hematological parameters which can be affected by many factors for the presence, severity and recurrence risk of nasal polyposis, and literature data should be proven by conducting different and objective studies on this subject.Yayın Comparison of clinical outcomes of three different packing materials in the treatment of severe acute otitis externa(Cambridge University Press, 2018) Demir, Deniz; Yılmaz, Mahmut Sinan; Güven, Mehmet; Kara, Ahmet; Elden, Halil; Erkorkmaz, Ünal; Demir, DenizObjective To analyse the clinical outcomes of biodegradable synthetic polyurethane foam versus ribbon gauze and ear wick in the treatment of severe acute otitis externa. Methods Ninety-two adults with severe acute otitis externa were randomly assigned to groups receiving ear wick (n = 28), ribbon gauze (n = 34) or biodegradable synthetic polyurethane foam (n = 30). Clinical efficacy, in terms of otalgia, oedema, erythema and tenderness of the external auditory canal, was assessed before packing was applied and at follow up on the 3rd and 7th days of presentation. Results All packing materials were associated with improved otalgia and oedema on the 3rd day; however, there were significant differences between biodegradable synthetic polyurethane foam and the other packing materials, and there was no significant reduction in tenderness in the biodegradable synthetic polyurethane foam group on the 3rd day. In the ribbon gauze and ear wick groups, improvements in all clinical efficacy scores were statistically significant for all pairwise comparisons. Conclusion The three packing materials were all quite effective in treating severe acute otitis externa, but ear wick and ribbon gauze were superior to biodegradable synthetic polyurethane foam for relieving signs and symptoms, especially on the 3rd day.Yayın Comparison of two different bone anchored hearing instruments: Baha-5 vs Ponto-plus(Taylor & Francis Online, 2019) Kara, Ahmet; Güven, Mehmet; Yılmaz, Mahmut Sinan; Demir, Deniz; Adigul, Çağlayan; Durgut, Merve; Elden, Halil; Mutlu, Fatih; İşeri, Mete; Demir, DenizBackground: To our knowledge, there is no study comparing Ponto Plus® (Oticon Medical AB, Askim, Sweden) and Baha® 5 (Cochlear Bone Anchored Solutions AG, Mölnlycke, Sweden) available in the literature. Aims/objectives: The primary aim was to compare the performance of the Baha 5 with the Ponto Plus device in terms of speech understanding in quiet and in noise. In addition, to determine statistically whether or not the difference between the abutment systems created any variation in terms of skin reaction. Materials and methods: Twenty bone-anchored hearing instrument users, ten in each group, were evaluated for speech understanding in quiet and several signal-to-noise ratios using the Turkish Matrix Test in a two-speaker setup. The Holger classifications were also reviewed to determine adverse skin reactions. Results: It was revealed that the hearing results of both devices were similar and, when the skin reactions were compared, there was no statistically significant difference between the two-implant systems. Conclusions and significance: Because of the similar results of the groups, it can be interpreted as the key different device features such as the size, weight, colour alternatives, and the ease of use of the devices might be important in terms of device preference.Yayın Evaluation of nasal tip shape in patients with severe caudal septal deviation after modified extracorporeal endonasal septoplasty(Elsevier, 2021) Demir, Deniz; Elden, Halil; Güven, Mehmet; Yılmaz, Mahmut Sinan; Kara, Ahmet; Demir, DenizObjectives The aim of this prospective study was to evaluate the effect of modified extracorporeal endonasal septoplasty on nasal tip shape and function in patients with severe caudal septal deviation. Methods The study population comprised of 55 patients undergoing modified extracorporeal endonasal septoplasty, which called marionette septoplasty. To analyse the aesthetic objective outcomes, postoperative photographs were measured for projection index (PI), tip projection (TP), nasolabial angle (NLA), tip deviation angle (TDA), nasofrontal angle (NFA), supratip height (STH), columellar height (CH), at three times (2 weeks, 3, and 6 months after surgery) and were compared with preoperative photographs. Functional and aesthetic outcomes were also evaluated using nasal obstruction symptom evaluation (NOSE) scale and standardized cosmesis and health nasal outcomes survey (SCHNOS). Results Between the pre- and post-operative 6th-month examinations, a significant increase in PI and TP were 7%, and 5% respectively. There was a significant alteration in the NLA and TDA values following the last examination (mean difference ± standard error of mean 9.68 ± 0.9° and 1.5 ± 0.8°, respectively). Moreover, the technique did not make a significant change in the final NFA, STH, and CH, measurements. Following surgery, the NOSE and SCHNOS scores were decreased significantly and the improvement continued over time until the last examination. Conclusion The present study findings suggest that the marionette septoplasty technique is an effective to correct and stabilize severe caudal septal deviations. This technique also can provide tip support and protection with a low incidence of dorsal irregularity.Yayın Impact of tonsillectomy on COVID–19 pandemic: an observational study of the incidence and prognosis(Taylor & Francis Online, 2021) Kara, Ahmet; Elden, Halil; Okur, Engin; Yılmaz, Mahmut Sinan; Mutlu, Fuldem; Güven, Mehmet; Demir, Deniz; Demir, DenizBackground Due to many different reasons such as possible coronavirus colonization in tonsillar tissue, decreased enzymatic antiviral activity, decreased cytokine activity from palatine tonsil tissue and reduced humoral and cellular immune response, tonsillectomy may alter the incidence of Covid–19. Aims/Objectives To reveal the frequency of Covid–19 in patients who underwent tonsillectomy and to analyze the effect of tonsillectomy on the severity of the disease. Materials and methods Patients aged between 15 and 65 and had a history of tonsillectomy were compared with control group in terms of incidence and severity of Covid–19 disease. Results A 4% Covid rRT–PCR test positivity rate was detected in patients with tonsillectomy whereas; it was 6.8% in the control group with a statistically significant difference. However, in terms of disease severity there was no difference between the two groups. Conclusions and significance It has been proven that tonsillectomy surgery does not pose an additional risk in terms of COVID 19 disease severity. The positive effect of tonsillectomy in terms of disease frequency has been even demonstrated for the first time in the literature.Yayın Paranazal sinüs bilgisayarlı tomografi incelemeleri ile keros sınıflaması ve kribriform plate derinliği asimetrisinin değerlendirilmesi(Sakarya Üniversitesi, 2018) Kara, Ahmet; Elden, Halil; Güven, Mehmet; Yılmaz, Mahmut Sinan; Demir, Deniz; Demir, DenizAmaç: Bu radyo-anatomik çalışma ile bölgemizdeki 18 yaş altı ve üstü populasyonun anterior kafa tabanı anatomisi ile ilgili veri elde etmek ve normatif verilerin elde edilmesi ile komplikasyon oranlarının azaltılması amaçlanmıştır. Gereç ve Yöntemler: Çalışmaya 7-18 yaş arası 100 kişi, 18-50 yaş arası 100 kişi olmak üzere toplam 200 kişi dahil edildi. Koronal planda çekilmiş bilgisayarlı tomografi görüntüleri dijital ortamda kemik pencerede incelendi. Olfaktor fossa derinlik ölçümleri yapıldı ve sonuçlar istatistiki yöntemler ile karşılaştırıldı. Bulgular: Pediatrik grubun yaş ortalaması 13.4±2.73 (erkek: 13.1±2.63, bayan: 13.6±2.82), erişkin grubun yaş ortalaması 39.9±7.46 (erkek: 40.6±7.82, bayan: 39.3±7.11) idi. Pediatrik ve erişkin grup lamina lateralis derinlikleri açısından karşılaştırıldığında aradaki fark istatistiki anlam oluşturmadı. Yine pediatrik ve erişkin gruplar kendi içlerinde cinsiyet farklılığı, sağ ve sol taraf asimerisi bakımından karşılaştırıldığında istatistiki anlamlı fark oluşmadı. Pediatrik grupta %15, erişkin grupta %18 oranında keros asimetrisi tespit edildi. Sonuç: Çalışmada gerçekleştirilen ölçümler sonucunda istatistiki olarak anlam ifade etmese de asimetrik keros vakaları konusunda cerrahın dikkatli olması gerekliliği literatür ile uyumlu bir şekilde tekrar vurgulanmıştır. Pediatrik yaş grubundaki farklılıklar için ise geniş katılımcı sayıları ile çalışmanın tekrarlanması önerilebilir
