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Yayın Absence of left anterior descending artery associated with atherosclerotic heart disease(WESTMINSTER PUBL INC, 2001) Ogus, NT; Cicek, S; Isik, O…Yayın Accelerated atherosclerosis in tertiary syphilis and successful treatment with saphenous vein grafting - A case report(SAGE PUBLICATIONS INC, 2001) Ogus, NT; Cakalagaoglu, C; Cakalagaoglu, F; Cicek, SA 48-year-old male patient having none of the known risk factors for atherosclerosis underwent coronary artery bypass graft (CABG) surgery because of double-vessel coronary artery disease. During the operation, the aorta, both internal thoracic arteries (L/R-ITA), and the femoral artery were sclerotic, and CABG was performed using only saphenous vein grafts. A diagnosis of tertiary syphilis had been confirmed by either microscopic or serologic tests. There were different degrees of sclerosis in different arteries of different sizes. The presence of coronary artery disease with no known atherosclerotic risk factors should include preoperative testing for connective tissue disorders, chronic inflammatory disease, and cold hemagglutinins, because of the possible use of obligatory deep hypothermia or total circulatory arrest due to a diseased ascending aorta.Yayın Prevention of recurrent osteomyelitis using cyanoacrylate gluing in mediastinitis(ELSEVIER SCIENCE INC, 2000) Ogus, NT; Emir, M; Cicek, S; Isik, O…Yayın Sternal cyanoacrylate gluing in mediastinitis - Effects on infection, stability and bone healing(EDIZIONI MINERVA MEDICA, 2002) Ogus, TN; Us, MH; Cicek, S; Ozkan, S; Ozturk, OY; Isic, OBackground It is crucial to determine stability, histocompatibility and antibacterial properties of the cyanoacrylate used for sternal fixation. Methods. Clinical study: in 17 cases of mediastinitis, debridement and rewiring the sternum, was applied as the treatment method (Group I). Eighteen cases of mediastinitis were treated with the same method added sternal cyanoacrylate gluing (Group 11). A comparative study was done;, the follow-up period was 36.7 +/- 4 and 18.5 +/- 6.9 months in Group I and H, respectively. Animal study: in 10 rats, upper sternotomy was done and the sternal bone was contaminated. Direct wound closure was done in 4 rats (Group A), in 6 animals, wounds were dosed after applying cyanoacrylate in sternal split (Group B). in this prospective study, all rats alive were sacrificed at the 3rd and 8th weeks and sternums were examined histologically. Results. Clinical study: in Group 1, 6 patients required additional interventions due to recurrent sternal detachment and osteomyelitis (35.3%). In Group H neither osteomyelitis nor sternal detachment occurred, 3 patients required re-intervention related to cyanoacrylate histotoxicity. Hospital stay was higher in Group I than Group II (24.06 +/- 4.7 vs 14.16 +/- 3.98 days, respectively). Experimental study: all of the animals in Group A died of sepsis. In Group B all rats survived the procedure. At the 3rd week histologic evaluations showed that cyanoacrylate was not degraded, and no infection or foreign body reaction was observed. At the 8th week histologic examination showed that cyanoacrylate was completely degraded and replaced by connective tissue. Conclusions. Cyanoacrylate is effective in diminishing sternal wound complications and related cost and hospital stay of mediastinitis.