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    THE EFFECT OF BREASTFEEDING ON THE RATE OF INFECTIONS IN THE THE FIRST 2 YEARS OF LIFE
    (Bmj Publishing Group, 2019) Arda, Duygu Burcu; Gur, Emel; Erener-Ercan, Tuğba; Can, Gunay; Arvas, Ahmet
    [Abstract Not Available]
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    The Effect of Vitamin D Prophylaxis on 25-OH Vitamin D Levels in Children
    (Aves, 2021) Gül, İhsan; Gur, Emel; Ercan, Tuğba Erener; Can, Gunay
    Background: Vitamin D deficiency is a major public health problem. The aim of our study was to determine serum 25-hydroxyvitamin D levels among healthy children aged 3-36 months in a setting where vitamin D prophylaxis is a national policy for infants during the first year of life and among pregnant women. Methods: A total of 190 healthy children with a mean age of 15.9 +/- 10.4 months were prospectively enrolled. Results: The mean 25-hydroxyvitamin D level of children was 38.1 +/- 16.2 ng/mL. 25-Hydroxyvitamin D level was >= 20 ng/mL in 87.4% of children while it was between 12 and 19 ng/mL in 10.5% and <12 ng/mL in 2.1% of the children. Children who were on vitamin D prophylaxis were found to have significantly higher 25-hydroxyvitamin D levels than those who were not on prophylaxis (41.6 +/- 17.6 vs 33.6 +/- 13.1 ng/mL; P = .001). None of the children >1 year of age who were on prophylaxis had 25-hydroxyvitamin D levels <20 ng/mL. No significant difference in 25-hydroxyvitamin D levels was found between children who were receiving different vitamin D doses (400 IU vs >400 IU). Analysis of covariance revealed that vitamin D prophylaxis and vitamin D supplementation of the mother during lactation had significant effects on 25-hydroxyvitamin D levels (P = .034 and P = .009, respectively). Conclusion: Although vitamin D prophylaxis at a dose of 400 IU seems to be sufficient to prevent vitamin D deficiency, we suggest that continuing vitamin D supplementation beyond 1 year of age with supplementation of pregnant and especially lactating mothers could have an impact on a replete vitamin D status among infants.
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    Vaccination Status in Children with Chronic Diseases: Are They Up-to-Date for Mandatory and Specific Vaccines?
    (Aves, 2023) Yirgin, Kübra; Gur, Emel; Erener-Ercan, Tuğba; Can, Gunay
    Objective: The aim of this study is to investigate the immunization coverage for mandatory and specific vaccines in a group of children with chronic diseases.Materials and Methods: Children with chronic diseases aged 6 months to 18 years who were followed up by outpatient subspecialty clinics of a tertiary hospital were enrolled. Children who were up-to-date and who were under-vaccinated were compared with respect to demo-graphic characteristics, parental educational status, healthcare providers' attitudes toward vaccination, age at the time of diagnosis, and duration of follow-up.Results: A total of 366 patients with variable chronic diseases were enrolled. Of these, 84.7% were up-to-date for the mandatory vaccines. This rate was 99.5% for the primary series of dipht heria -teta nus-a cellu lar pertussis and 98.9% for the first dose of measles-mumps-rubella vaccines. Vaccination coverage for specific vaccines was low (13.9% for influenza and 55% for conjugated pneumococcal vaccine). Being older at the time of diagnosis increased the likeli-hood of being up-to-date for mandatory vaccines by 1.1 times, while being followed up from multiple subspecialty outpatient clinics and attendance to private doctors' clinics for vaccina-tion increased the likelihood of being up-to-date for specific vaccines by 19.1 and 6.4 times, respectively.Conclusion: In this study, immunization coverage for mandatory vaccines was comparable to that of the general population. However, vaccination coverage was low for specific vaccines. Therefore, efforts of prioritization of pediatric immunizations and raising awareness among healthcare providers about the impact of medical recommendations for specific vaccines among children with chronic diseases can help to improve vaccination rates.