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    Gallstones and Concomitant Gastric Helicobacter pylori Infection
    (HINDAWI LTD, 2013) Attaallah, Wafi; Yener, Nese; Ugurlu, M. Umit; Manukyan, Manuk Norayık; Asmaz, Ebru; Aktan, A. Ozdemir
    Background. The association of gallstones with Helicobacter pylori has been investigated but not clearly demonstrated. In this study, the presence of H. pylori in the gallbladder mucosa of patients with symptomatic gallstones was investigated. Method. Ninety-four consecutive patients with symptomatic gallstone disease were enrolled for the study. Gastroscopy and gastric H. pylori urease test were done before cholecystectomy to all patients who accepted. After cholecystectomy, the gallbladder tissue was investigated in terms of H. pylori by urease test, Giemsa, and immunohistochemical stain. Results. Overall 35 patients (37%) gallbladder mucosa tested positive for H. pylori with any of the three tests. Correlation of the three tests Giemsa, IHC, and rapid urease test was significant (r(s): 0590, P > 0.001). Rapid urease test was positive in the gastricmucosa in 47 (58.7%) patients, and it was positive in the gallbladder mucosa in 21 patients (22%). In 15 patients both gastric and gallbladder tested positive with the urease test. There was significant correlation of rapid urease test in both of gallbladder and gastric mucosa (P = 0.0001). Conclusion. Study demonstrates the presence of H. pylori in the gallbladders of 37% of patients with symptomatic gallstones.
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    Is hemithyroidectomy a rational management for benign nodular goitre? a multicentre retrospective single group study
    (Van Zuiden Communications BV, 2015) Attaallah, Wafi; Erel, Serap; Cantürk, Nuh Zafer; Erbil, Yeşim; Görgülü, Semih; Kulaçoğlu, Hakan; Koçdor, Mehmet Ali; Kebudi, Abut; Özbaş, Serdar Mustafa; Güllüoğlu, Bahadır M.
    Background: The incidence and potential risk factors for the recurrence of benign nodular goitre after unilateral thyroidectomy are not clearly defined. The aim of this study was to assess the rate of progression of nodular goiter in the contralateral thyroid lobe and of hypothyroidism requiring replacement therapy after unilateral thyroidlobectomy for benign nodular goitre.Patients and Methods: Patients who underwent hemithyroidectomy for benign nodular goitre between 2000 and 2009 were included in the study. The primary outcome of this study was the reoperation rate for recurrent goitre, the rate of progression of nodular goitre and the rate of hypothyroidism requiring L-T4 replacement therapy. Clinical factors that have an effect on progression were further analysed.Results: 259 patients were included for study. Progression of the nodular goitre in the remnant lobe was observedin 32% (n = 83) of the patients. However, over time,only 2% of these 83 patients underwent contralateral hemithyroidectomy due to this progression. Fifty-six (22%) patients required L-thyroxin replacement due topersistent hypothyroidism after hemithyroidectomy. The factors shown to affect progression of nodular goiter were advanced age, preoperative hyperthyroidism,preoperative diagnosis of toxic nodular goitre and the presence of surgical indication for a toxic goitre causing hyperthyroidism and a definitive pathological diagnosis of nodular hyperplasia.Conclusion: There was a progression of the nodular goiter in the remnant lobe in about one-third of the patients who underwent hemithyroidectomy. However, only 2% of these patients underwent complementary contralateral hemithyroidectomy due to clinical progression in 31months of follow-up. © Van Zuiden Communications B.V. All rights reserved.
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    Prospective Randomized Comparison of Oral Sodium Phosphate and Sennoside A plus B Calcium Lavage for Colonoscopy Preparation
    (LIPPINCOTT WILLIAMS & WILKINS, 2011) Manukyan, Manuk Norayık; Tolan, Kerem; Severge, Utku; Attaallah, Wafi; Kebudi, Abut; Cingi, Asim
    Purpose: The aim of this study is to assess 2 different bowel-cleansing agents. Methods: The patients were prospectively randomized to 2 arms of sodium phosphate versus Sennoside A+B calcium preparation. Laboratory assessment, body weight, height, and vital signs were obtained at baseline and before colonoscopy. A self-administered questionnaire was completed by the patients. The time taken to complete the colonoscopy and the segment of the colon examined were recorded. Results: The patients in the Sennoside A+B calcium group were more comfortable with the taste of the solution. Patients using sodium phosphate faced more nausea and significantly lower Ca levels and P values. The pulse rate was significantly higher in this group. Patients in the sennoside group had better grades of bowel cleansing in sigmoid and descending segments of the colon. Conclusions: Sennoside A+B calcium is more effective in some of the colonic segmental cleansing, causes fewer changes on serum electrolyte levels, and is better tolerated.